RBM15B and ITIH1

		RBM15B	ITIH1
Description		RNA binding motif protein 15B	inter-alpha-trypsin inhibitor heavy chain 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nucleoplasm Nucleolus Nuclear Speck RNA N6-methyladenosine Methyltransferase Complex	Extracellular Region Collagen-containing Extracellular Matrix Extracellular Exosome Blood Microparticle
	Molecular Function	RNA Binding MRNA Binding Protein Binding	Serine-type Endopeptidase Inhibitor Activity Calcium Ion Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome RNA Methylation MRNA Processing MRNA Export From Nucleus Nucleocytoplasmic Transport RNA Splicing Dosage Compensation By Inactivation Of X Chromosome Negative Regulation Of Transcription, DNA-templated	Negative Regulation Of Endopeptidase Activity Hyaluronan Metabolic Process
Pathways
Drugs			Zinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29679657) Apolipoprotein A1 levels ( 33730874)	Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972 19416921 33263727 31043756) Blood protein levels ( 29875488) Body mass index ( 25673413) Body shape index ( 34021172) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cortical surface area (MOSTest) ( 32665545) General cognitive ability ( 29844566) Glaucoma (primary open-angle) ( 25173105) Osteoarthritis (hip) ( 30374069) Pulse pressure ( 30578418) Schizophrenia ( 25056061 29483656 23974872) Schizophrenia, schizoaffective disorder or bipolar disorder ( 24166486) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for body mass index ( 34021172 28448500) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for body mass index ( 28448500)
Interacting Genes		14 interacting genes: AMT ATP6V0D2 CDC23 DVL3 EGR2 ERBB2 IMPDH2 ITIH1 NAV2 NXF1 PTEN SRPK2 TNNC1 TRIM54	8 interacting genes: ARF4 ARIH2 CALR HSP90AA1 PHAX PIK3CA RBM15B SOX4
Entrez ID		29890	3697
HPRD ID		11486	00927
Ensembl ID		ENSG00000259956	ENSG00000055957
Uniprot IDs		Q8NDT2	B7Z8B6 P19827
PDB IDs			6FPY 6FPZ
Enriched GO Terms of Interacting Partners?
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