ZDHHC1 and GOPC

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ZDHHC1	GOPC
Description		zinc finger DHHC-type containing 1	golgi associated PDZ and coiled-coil motif containing
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Endosome Membrane Integral Component Of Membrane Extracellular Exosome	Golgi Membrane Cytoplasm Lysosomal Membrane Golgi Apparatus Plasma Membrane Postsynaptic Density Membrane Trans-Golgi Network Transport Vesicle Dendrite Golgi-associated Vesicle Membrane Protein-containing Complex
	Molecular Function	DNA Binding Protein Binding Palmitoyltransferase Activity Protein-cysteine S-palmitoyltransferase Activity	Protein Binding Identical Protein Binding Transmembrane Transporter Binding
	Biological Process	Positive Regulation Of Defense Response To Virus By Host Protein Targeting To Membrane Peptidyl-L-cysteine S-palmitoylation Protein Palmitoylation Antiviral Innate Immune Response	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Transport Negative Regulation Of Anion Channel Activity Protein Transport Cytoplasmic Sequestering Of CFTR Protein Apical Protein Localization Negative Regulation Of Protein Localization To Cell Surface
Pathways			RHO GTPases regulate CFTR trafficking RHOQ GTPase cycle
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Body size at age 10 ( 32376654) Bone mineral density ( 31790847) Empathy quotient ( 29527006) Refractive error ( 32231278) Waist-to-hip ratio adjusted for body mass index ( 28430825)	Atrial fibrillation ( 29892015) Colorectal cancer ( 23266556) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Facial emotion recognition (fearful faces) ( 28608620) Night sleep phenotypes ( 27126917)
Interacting Genes		17 interacting genes: CYSRT1 GOPC KRT31 KRT34 KRT83 KRTAP1-1 KRTAP1-3 KRTAP10-8 KRTAP12-2 KRTAP12-3 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP9-2 MDFI NBPF19 NOTCH2NLA	71 interacting genes: ABCA1 ADRB1 AKIRIN1 ASIC3 ATG9A BATF BECN1 C17orf67 CCDC102B CCDC198 CD300C CDKN2C CERCAM CFTR CLCN3 CRHR1 CSPG5 DLEU1 DPYD FAM90A1 FAM9B FOSL2 FZD5 FZD8 GEM GOLGA3 GRID1 GRID2 HCK HNRNPLL IGHG3 JUN KPNA1 LCLAT1 MORN4 MRPL1 MYLK MYOCD NOTCH1 NUP62 OSBP2 PARK7 PID1 PPP1R18 PWWP3A RALGAPB RELA RHOQ RNF183 RNF220 RPL13AP17 RPS6KA1 RTKN SEMA4G SLC25A18 SNX31 SPATA8 SSTR5 STARD3 STX6 TGFBR2 TUBE1 VIM VTN ZBTB49 ZDHHC1 ZNF564 ZNF581 ZNF587 ZNF835 ZSCAN1
Entrez ID		29800	57120
HPRD ID		15707	06024
Ensembl ID		ENSG00000159714	ENSG00000047932
Uniprot IDs		I3L202 Q8WTX9	Q9HD26
PDB IDs			2DC2 2LOB 4E34 4E35 4JOE 4JOF 4JOG 4JOH 4JOJ 4JOK 4JOP 4JOR 4K6Y 4K72 4K75 4K76 4K78 4NMO 4NMP 4NMQ 4NMR 4NMS 4NMT 4NMV 4Q6H 4Q6S 5IC3 5K4F 6OV7 6V84 6XNJ
Enriched GO Terms of Interacting Partners?
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