GRP and MEP1B

Number of citations of the paper that reports this interaction (PubMedID 11278902)
44

Data Source:
HPRD (in vitro)

		GRP	MEP1B
Description		gastrin releasing peptide	meprin A subunit beta
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Secretory Granule Lumen	Extracellular Region Integral Component Of Plasma Membrane Meprin A Complex
	Molecular Function	Signaling Receptor Binding Neuropeptide Hormone Activity Protein Binding	Metalloendopeptidase Activity Protein Binding Zinc Ion Binding Identical Protein Binding
	Biological Process	Signal Transduction Neuropeptide Signaling Pathway Social Behavior Psychomotor Behavior Response To External Biotic Stimulus Positive Regulation Of Peptide Hormone Secretion Positive Regulation Of Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway	Proteolysis Inflammatory Response Toxin Transport
Pathways		Peptide ligand-binding receptors Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) G alpha (q) signalling events
Drugs
Diseases
GWAS		Adult body size ( 32376654) BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) Body mass index ( 25673413) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Medication use (drugs used in diabetes) ( 31015401) Pancreas volume ( 34128465) Pancreatic cancer ( 29422604 26098869) Pancreatic ductal adenocarcinoma ( 30541042) Triglyceride levels x thiazide or thiazide-like diuretics use interaction ( 31806883) Type 2 diabetes ( 30297969) Venous thromboembolism ( 32232851)	Metabolite levels ( 23823483) TRAIL levels ( 27989323)
Interacting Genes		5 interacting genes: ALX1 DPP4 GRPR MEP1A MEP1B	12 interacting genes: CCK FN1 GAST GCG GRP MEP1A NPY OS9 PRKACA PRKCD PYY SCT
Entrez ID		2922	4225
HPRD ID		08845	02667
Ensembl ID		ENSG00000134443	ENSG00000141434
Uniprot IDs		A0A140VJM7 P07492	J3QKX5 Q16820
PDB IDs		2N0B 2N0C 2N0D 2N0E 2N0F 2N0G 2N0H	4GWM 4GWN 7AQ1
Enriched GO Terms of Interacting Partners?
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