LGALS13 and PACSIN3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		LGALS13	PACSIN3
Description		galectin 13	protein kinase C and casein kinase substrate in neurons 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Nuclear Matrix Nuclear Body	Cytoplasm Endosome Cytosol Plasma Membrane Extracellular Exosome
	Molecular Function	Lysophospholipase Activity Protein Binding Carbohydrate Binding	Protein Binding Phospholipid Binding Cytoskeletal Protein Binding Lipid Binding Calcium Channel Inhibitor Activity Identical Protein Binding
	Biological Process	Phospholipid Metabolic Process Apoptotic Process Positive Regulation Of T Cell Apoptotic Process	Endocytosis Cytoskeleton Organization Regulation Of Endocytosis Negative Regulation Of Endocytosis Positive Regulation Of Membrane Protein Ectodomain Proteolysis Negative Regulation Of Calcium Ion Transport Plasma Membrane Tubulation
Pathways			Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Lead levels ( 26025379)	Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Autism spectrum disorder or schizophrenia ( 28540026) Waist-to-hip ratio adjusted for body mass index ( 26785701)
Interacting Genes		11 interacting genes: ACTB ACTG1 ANXA2 CREB5 HOXA1 NUFIP2 OTX1 PACSIN3 PHLDA1 POU3F2 POU4F2	25 interacting genes: ADAM12 ADAM15 ASAP1 ASAP2 ATXN7L2 CLNK DNM1 ITSN1 KRTAP12-2 LGALS13 OGT PACSIN1 PACSIN2 PAK2 RAF1 SMARCD1 SOS1 SOS2 SPRY2 SYNJ1 TERF2IP TNFSF4 TNPO2 TRPV4 WASL
Entrez ID		29124	29763
HPRD ID		16375	05937
Ensembl ID		ENSG00000105198	ENSG00000165912
Uniprot IDs		Q9UHV8	Q9UKS6
PDB IDs		1F87 5XG7 5XG8 5Y03 6A62 6A63 6A64 6A65 6A66 6KJW 6KJX 6KJY
Enriched GO Terms of Interacting Partners?
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