TBK1 and IRF5

  • Number of citations of the paper that reports this interaction (PubMedID 15695821)
  • 143
  • Data Source:
  • HPRD (in vitro, in vivo)

TBK1

IRF5

Description TANK binding kinase 1 interferon regulatory factor 5
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Amyotrophic lateral sclerosis ( 29566793 27455348)
  • High light scatter reticulocyte count ( 32888494)
  • High light scatter reticulocyte percentage of red cells ( 32888494)
  • Lung adenocarcinoma ( 28604730)
  • Reticulocyte count ( 32888494)
  • Reticulocyte fraction of red cells ( 32888494)
Interacting Genes 53 interacting genes: AGAP2 AGO2 APP ATG9A AVIL AZI2 CALCOCO2 CDC37 CDC42BPG CRTC1 CYLD HSP90AA1 HSP90AB1 IKBKB IKBKG IRF3 IRF5 IRF7 MAP1LC3B MARCHF9 MAVS MBP MIB2 MPP3 MTPAP NCK1 NEDD4 NFKBIA PROS1 PTPRD RELA RIPK1 RNF128 RPS6KB1 SCN7A SIKE1 SMCR8 SMURF1 SOCS2 SQSTM1 STX11 TANK TICAM1 TRAF2 TRAF3 TRAF3IP2 TRAF5 TRIM21 TRIM27 TXLNG UBQLN2 XIAP YAF2 21 interacting genes: ALPI COPS3 CPA2 CREBBP EP300 HDAC1 IKBKE IRF3 LRRC61 MAVS MEST MYD88 NCOR2 NDUFA5 SGTA SIN3A TBK1 TRAF6 TRIM15 TRIM21 XPO1
Entrez ID 29110 3663
HPRD ID 05322 06240
Ensembl ID ENSG00000183735 ENSG00000128604
Uniprot IDs Q9UHD2 A0A0G2USB5 B7Z1M2 C9JAU6 Q13568
PDB IDs 4EFO 4EUT 4EUU 4IM0 4IM2 4IM3 4IW0 4IWO 4IWP 4IWQ 5EOA 5EOF 5EP6 5W5V 6BNY 6BOD 6BOE 6CQ0 6CQ4 6CQ5 6NT9 6O8B 6RSR 6RST 6RSU 3DSH
Enriched GO Terms of Interacting Partners?
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