GRIK1 and TAAR1

Number of citations of the paper that reports this interaction (PubMedID 28298427)
23

Data Source:
BioGRID (two hybrid)

		GRIK1	TAAR1
Description		glutamate ionotropic receptor kainate type subunit 1	trace amine associated receptor 1
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Postsynaptic Membrane	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Glutamate Receptor Activity Ligand-gated Ion Channel Activity Kainate Selective Glutamate Receptor Activity Signaling Receptor Activity Transmitter-gated Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential	Trace-amine Receptor Activity G Protein-coupled Receptor Activity
	Biological Process	Glutamate Receptor Signaling Pathway Chemical Synaptic Transmission Nervous System Development Central Nervous System Development Ion Transmembrane Transport Ionotropic Glutamate Receptor Signaling Pathway Synaptic Transmission, Glutamatergic Modulation Of Chemical Synaptic Transmission Regulation Of Synaptic Transmission, Glutamatergic Regulation Of Postsynaptic Membrane Potential	G Protein-coupled Receptor Signaling Pathway
Pathways		Activation of Na-permeable kainate receptors Activation of Ca-permeable Kainate Receptor	Amine ligand-binding receptors G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production
Drugs		Glutamic acid Butabarbital Topiramate Tezampanel	Amphetamine Lisdexamfetamine Dextroamphetamine Metamfetamine Propylhexedrine SEP-363856
Diseases
GWAS		Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885) Body mass index ( 22446040) Breast cancer ( 17903305) Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444) Forehead morphology ( 29921221) Generalized epilepsy ( 30531953) Glucocorticoid-induced osteonecrosis ( 26265699) HDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883) Hepatocellular carcinoma ( 22807686) Hyperactive-impulsive symptoms ( 18821565) Lung cancer ( 34062886) Periodontitis (DPAL) ( 24024966) Plasma parathyroid hormone levels ( 30134803) Refractive error ( 32231278) Response to statin therapy ( 20339536) Spherical equivalent or myopia (age of diagnosis) ( 29808027)	Compulsion score in obsessive compulsive disorder ( 32063569)
Interacting Genes		9 interacting genes: CYSLTR2 DLG4 FLNA GRIP1 HOMER1 IFNGR2 PICK1 SDCBP TAAR1	4 interacting genes: GRIK1 PCMT1 RNASEK SVOP
Entrez ID		2897	134864
HPRD ID		00693	18142
Ensembl ID		ENSG00000171189	ENSG00000146399
Uniprot IDs		B7Z256 B7Z3V7 E7ENK3 E7EPY9 E7EPZ0 E9PD61 P39086	Q96RJ0
PDB IDs		2ZNS 2ZNT 2ZNU 3FUZ 3FV1 3FV2 3FVG 3FVK 3FVN 3FVO 4MF3
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?