LAMTOR2 and BORCS6

Number of citations of the paper that reports this interaction (PubMedID 28514442)
406

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		LAMTOR2	BORCS6
Description		late endosomal/lysosomal adaptor, MAPK and MTOR activator 2	BLOC-1 related complex subunit 6
Image			No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Late Endosome Plasma Membrane Endosome Membrane Specific Granule Membrane Tertiary Granule Membrane Ragulator Complex	Lysosomal Membrane BORC Complex
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Molecular Adaptor Activity	Protein Binding Identical Protein Binding
	Biological Process	Regulation Of Cell Growth Fibroblast Migration Positive Regulation Of TOR Signaling Cellular Protein Localization Positive Regulation Of MAPK Cascade Regulation Of Catalytic Activity Cellular Response To Amino Acid Stimulus Regulation Of Cell-substrate Junction Organization Protein Localization To Cell Junction	Lysosome Localization
Pathways		Macroautophagy MTOR signalling mTORC1-mediated signalling Energy dependent regulation of mTOR by LKB1-AMPK TP53 Regulates Metabolic Genes MAP2K and MAPK activation Neutrophil degranulation Regulation of PTEN gene transcription Amino acids regulate mTORC1
Drugs
Diseases
GWAS
Interacting Genes		3 interacting genes: BORCS6 ERBB3 LAMTOR3	35 interacting genes: ABI2 BEX2 C19orf25 C1orf109 C1orf216 DISC1 EPS8 EXOC8 EXOSC5 FAM161B FAM9C FBXO44 FCHSD2 GAS8 HAUS1 HGS INSYN1 KANK2 KXD1 LAMTOR2 LNX1 MED21 MOS NDEL1 NTAQ1 OSTF1 PKNOX1 PLA2G4A RCOR3 RIBC1 SHPRH SPG21 TACC2 USHBP1 ZNF655
Entrez ID		28956	54785
HPRD ID		17463	13368
Ensembl ID		ENSG00000116586	ENSG00000196544
Uniprot IDs		Q9Y2Q5	Q96GS4
PDB IDs		5X6U 5X6V 5Y39 5Y3A 6B9X 6EHP 6EHR 6NZD 6U62 6ULG 6WJ2 6WJ3
Enriched GO Terms of Interacting Partners?
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