REM1 and CACNB1

Number of citations of the paper that reports this interaction (PubMedID 14623965)
81

Data Source:
HPRD (in vivo)

		REM1	CACNB1
Description		RRAD and GEM like GTPase 1	calcium voltage-gated channel auxiliary subunit beta 1
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane	Plasma Membrane Voltage-gated Calcium Channel Complex Sarcolemma Synapse
	Molecular Function	GTPase Activity Calcium Channel Regulator Activity Calmodulin Binding GTP Binding	Voltage-gated Calcium Channel Activity Protein Binding High Voltage-gated Calcium Channel Activity
	Biological Process	Negative Regulation Of High Voltage-gated Calcium Channel Activity	Chemical Synaptic Transmission Neuromuscular Junction Development Calcium Ion Transmembrane Transport Regulation Of Voltage-gated Calcium Channel Activity Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel Cellular Response To Amyloid-beta
Pathways			Presynaptic depolarization and calcium channel opening NCAM1 interactions Phase 0 - rapid depolarisation Phase 2 - plateau phase
Drugs			Ergocalciferol Enflurane Ranolazine Phenytoin Topiramate Ibutilide Amlodipine Nimodipine Spironolactone Magnesium sulfate Levomenthol Ethanol Miconazole Amiodarone Mibefradil Dronedarone Trimebutine Azelnidipine Benidipine Cilnidipine Lacidipine Manidipine Butamben Bioallethrin Bioallethrin Fish oil
Diseases
GWAS			Asthma ( 31619474) Non-lobar intracerebral hemorrhage (MTAG) ( 31430377)
Interacting Genes		7 interacting genes: CACNB1 CACNB2 CACNB4 YWHAE YWHAH YWHAQ YWHAZ	8 interacting genes: APP ATN1 CACNA1A CTBP2 DYNLL1 NEDD4L REM1 SRPK1
Entrez ID		28954	782
HPRD ID		15237	11743
Ensembl ID		ENSG00000088320	ENSG00000067191
Uniprot IDs		O75628	Q02641
PDB IDs		2NZJ
Enriched GO Terms of Interacting Partners?
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