LYPD5 and TSPO

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		LYPD5	TSPO
Description		LY6/PLAUR domain containing 5	translocator protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Anchored Component Of Membrane	Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Cytosol Integral Component Of Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	Protein Binding	Androgen Binding Protein Binding Benzodiazepine Receptor Activity Cholesterol Binding Transmembrane Transporter Binding Cholesterol Transfer Activity
	Biological Process		Protein Targeting To Mitochondrion C21-steroid Hormone Biosynthetic Process Heme Biosynthetic Process Anion Transport Chloride Transport Aging Steroid Metabolic Process Glial Cell Migration Response To Xenobiotic Stimulus Response To Manganese Ion Response To Vitamin B1 Positive Regulation Of Necrotic Cell Death Peripheral Nervous System Axon Regeneration Sterol Transport Adrenal Gland Development Negative Regulation Of Protein Ubiquitination Regulation Of Cholesterol Transport Response To Progesterone Negative Regulation Of Tumor Necrosis Factor Production Response To Testosterone Regulation Of Cell Population Proliferation Positive Regulation Of Apoptotic Process Negative Regulation Of Nitric Oxide Biosynthetic Process Behavioral Response To Pain Regulation Of Steroid Biosynthetic Process Positive Regulation Of Mitochondrial Depolarization Positive Regulation Of Calcium Ion Transport Contact Inhibition Positive Regulation Of Glial Cell Proliferation Negative Regulation Of Glial Cell Proliferation Cellular Response To Lipopolysaccharide Cellular Response To Zinc Ion Cellular Hypotonic Response Maintenance Of Protein Location In Mitochondrion Intermembrane Lipid Transfer Negative Regulation Of Autophagy Of Mitochondrion Negative Regulation Of ATP Metabolic Process Positive Regulation Of Reactive Oxygen Species Metabolic Process
Pathways		Post-translational modification: synthesis of GPI-anchored proteins	Pregnenolone biosynthesis
Drugs			Chlormezanone Zopiclone
Diseases
GWAS		Breast cancer ( 29059683 23535729) Reading or mathematical ability ( 25003214)	Metabolite levels ( 23823483) Monocyte count ( 32888494 27863252) Monocyte percentage of white cells ( 32888494 27863252) White blood cell count ( 32888494)
Interacting Genes		8 interacting genes: BET1 EHHADH ERG28 ERMP1 IFITM3 NINJ2 PLPPR2 TSPO	18 interacting genes: AMIGO1 CLEC10A CREB3L1 DBI FAM209A FCER1G ICAM3 KCNF1 LEUTX LHFPL5 LYPD5 MEOX2 NCR3LG1 PVR TMEM14B TMEM9 TSPAN15 TSPOAP1
Entrez ID		284348	706
HPRD ID		08084	15913
Ensembl ID		ENSG00000159871	ENSG00000100300
Uniprot IDs		Q6UWN5	O76068 P30536
PDB IDs
Enriched GO Terms of Interacting Partners?
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