GP1BB and GSDME

		GP1BB	GSDME
Description		glycoprotein Ib platelet subunit beta	gasdermin E
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Cytoplasm Cytosol Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding Identical Protein Binding	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Cardiolipin Binding
	Biological Process	Cell Adhesion Cell Surface Receptor Signaling Pathway Platelet Activation	Sensory Perception Of Sound Cell Death Negative Regulation Of Cell Population Proliferation Positive Regulation Of MAPK Cascade Inner Ear Receptor Cell Differentiation Necrotic Cell Death Pyroptosis Cellular Response To Tumor Necrosis Factor Cellular Response To Virus Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways		Intrinsic Pathway of Fibrin Clot Formation GP1b-IX-V activation signalling Platelet Adhesion to exposed collagen Platelet Aggregation (Plug Formation) Defective F9 activation	Release of apoptotic factors from the mitochondria Pyroptosis Regulation of TLR by endogenous ligand Defective pyroptosis
Drugs
Diseases
GWAS		DNA methylation (parent-of-origin) ( 23725790) Mean platelet volume ( 32888494 27863252) Platelet count ( 32888494 27863252) Platelet distribution width ( 32888494 27863252)
Interacting Genes		5 interacting genes: GP9 GSDME PRKACA TGFB1I1 YWHAZ	11 interacting genes: AHR C1GALT1 GARS1 GP1BB GPNMB HNRNPA2B1 ITGB1BP1 PTN TBX19 TIFA VPS41
Entrez ID		2812	1687
HPRD ID		00729	02996
Ensembl ID		ENSG00000203618	ENSG00000105928
Uniprot IDs		P13224	A0A024RA58 A4FVA8 O60443
PDB IDs		3REZ 3RFE
Enriched GO Terms of Interacting Partners?
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