GNL1 and VPS35

Number of citations of the paper that reports this interaction (PubMedID 33305682)
2

Data Source:
BioGRID (unspecified method)

		GNL1	VPS35
Description		G protein nucleolar 1 (putative)	VPS35 retromer complex component
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleus	Mitochondrion Lysosome Lysosomal Membrane Endosome Early Endosome Late Endosome Cytosol Endosome Membrane Retromer Complex Retromer, Cargo-selective Complex Extracellular Exosome Tubular Endosome Mitochondrion-derived Vesicle
	Molecular Function	GTPase Activity Structural Molecule Activity GTP Binding	Protein Binding D1 Dopamine Receptor Binding
	Biological Process	T Cell Mediated Immunity Cellular Response To DNA Damage Stimulus Signal Transduction	Intracellular Protein Transport Positive Regulation Of Gene Expression Regulation Of Mitochondrion Organization Wnt Signaling Pathway Regulation Of Macroautophagy Regulation Of Protein Stability Regulation Of Cellular Protein Metabolic Process Endocytic Recycling Protein Localization To Endosome Retrograde Transport, Endosome To Golgi Mitochondrial Fragmentation Involved In Apoptotic Process Transcytosis Negative Regulation Of Inflammatory Response Positive Regulation Of Dopamine Receptor Signaling Pathway Negative Regulation Of Cell Death Positive Regulation Of Mitochondrial Fission Mitochondrion To Lysosome Transport Neurotransmitter Receptor Transport, Endosome To Plasma Membrane Negative Regulation Of Neuron Death Negative Regulation Of Late Endosome To Lysosome Transport Regulation Of Dendritic Spine Maintenance Positive Regulation Of Cellular Protein Catabolic Process Regulation Of Presynapse Assembly Regulation Of Terminal Button Organization
Pathways			WNT ligand biogenesis and trafficking
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Lung cancer ( 28604730) Major depressive disorder ( 27479909) Neuroticism ( 29255261) Rosacea symptom severity ( 29771307) Squamous cell lung carcinoma ( 28604730)
Interacting Genes		9 interacting genes: DAXX GDI1 KRT6A PRKN PTP4A1 SIRPA VPS35 YIF1A ZNF212	15 interacting genes: APP DRD1 GNL1 LINC01554 MTNR1B PRPF19 SLC11A2 SNX1 SNX3 VEGFA VPS26A VPS26B VPS29 YBX1 ZNF512B
Entrez ID		2794	55737
HPRD ID		00879	06085
Ensembl ID		ENSG00000204590	ENSG00000069329
Uniprot IDs		A0A024RCR2 B4DYK6 P36915	Q96QK1
PDB IDs			2R17 5F0J 5F0K 5F0L 5F0M 5F0P 5OSH 5OSI 7BLN 7BLO
Enriched GO Terms of Interacting Partners?
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