GLUL and RABEPK

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		GLUL	RABEPK
Description		glutamate-ammonia ligase	Rab9 effector protein with kelch motifs
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Rough Endoplasmic Reticulum Cytosol Plasma Membrane Protein-containing Complex Perikaryon Myelin Sheath Axon Terminus Extracellular Exosome Glial Cell Projection	Endosome Cytosol Endosome Membrane Transport Vesicle Trans-Golgi Network Membrane
	Molecular Function	Magnesium Ion Binding Glutamate-ammonia Ligase Activity Protein Binding ATP Binding Glutamate Binding Protein-cysteine S-palmitoyltransferase Activity Manganese Ion Binding Identical Protein Binding Dynein Light Chain Binding	Protein Binding
	Biological Process	Angiogenesis Glutamate Catabolic Process Glutamine Biosynthetic Process Cell Population Proliferation Cellular Response To Starvation Response To Glucose Regulation Of Endothelial Cell Migration Protein Palmitoylation Ammonia Assimilation Cycle Positive Regulation Of Insulin Secretion Ribosome Biogenesis Positive Regulation Of Epithelial Cell Proliferation Positive Regulation Of Synaptic Transmission, Glutamatergic Regulation Of Sprouting Angiogenesis Regulation Of Protein Localization To Nucleolus	Receptor-mediated Endocytosis Vesicle Docking Involved In Exocytosis
Pathways		Astrocytic Glutamate-Glutamine Uptake And Metabolism Glutamate and glutamine metabolism	Retrograde transport at the Trans-Golgi-Network
Drugs		L-Glutamine Glutamic acid
Diseases
GWAS		Cardiovascular heart disease in diabetics ( 23982368) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) HDL cholesterol levels ( 32203549) Morning person ( 30696823)	Refractive error ( 32231278)
Interacting Genes		22 interacting genes: CASP8AP2 CRBN CYP39A1 DYNLL1 EP300 HIPK1 HIPK3 HSD17B10 HTR2A MT-ND5 NFKB1 NUDT18 PIAS1 PIAS2 PIAS3 PLEKHF2 PPARD RABEPK RBBP6 SKIL TAT UBE2I	8 interacting genes: GLUL PIKFYVE POR PRKRA RAB9A TMEM98 TRIM55 ZYX
Entrez ID		2752	10244
HPRD ID		00701	09337
Ensembl ID		ENSG00000135821	ENSG00000136933
Uniprot IDs		A8YXX4 P15104	A0A024R8A0 A0A0S2Z4Z1 A0A0S2Z4Z5 Q7Z6M1
PDB IDs		2OJW 2QC8
Enriched GO Terms of Interacting Partners?
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