GLRX and AQP5

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		GLRX	AQP5
Description		glutaredoxin	aquaporin 5
Image
GO Annotations	Cellular Component	Nucleus Cytosol Extracellular Exosome	Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Microvillus Basal Plasma Membrane Integral Component Of Membrane Apical Plasma Membrane Cytoplasmic Vesicle Membrane Extracellular Exosome
	Molecular Function	Glutathione-disulfide Reductase (NADPH) Activity Protein Binding Glutathione Disulfide Oxidoreductase Activity Protein N-terminus Binding Glutathione Oxidoreductase Activity	Protein Binding Water Channel Activity Identical Protein Binding
	Biological Process	Nucleobase-containing Small Molecule Interconversion Positive Regulation Of Membrane Potential Protein Deglutathionylation Cellular Oxidant Detoxification Positive Regulation Of Sodium Ion Transmembrane Transporter Activity	Water Transport Carbon Dioxide Transport Pancreatic Juice Secretion Odontogenesis Saliva Secretion Camera-type Eye Morphogenesis Protein Homotetramerization Transmembrane Transport Cellular Hypotonic Response
Pathways		Interconversion of nucleotide di- and triphosphates	Passive transport by Aquaporins
Drugs		Glutathione
Diseases
GWAS		hemolysis of donated blood (oxidative) ( 34014839) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494 27863252) Metabolite levels ( 23823483) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252)	Allergic rhinitis ( 30013184) Asthma ( 32296059)
Interacting Genes		8 interacting genes: AQP5 CASP3 GOT2 MAP3K5 MMP23B NFIC PTPN1 TRIM62	9 interacting genes: CREB3 GLRX HNRNPK KRT31 KRT40 MDFI NOTCH2NLA TUBA1C WNT2
Entrez ID		2745	362
HPRD ID		02707	02706
Ensembl ID		ENSG00000173221	ENSG00000161798
Uniprot IDs		A0A024RAM2 P35754	P55064
PDB IDs		1B4Q 1JHB 4RQR	3D9S 5C5X 5DYE
Enriched GO Terms of Interacting Partners?
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