TMEM97 and PDCD1LG2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TMEM97	PDCD1LG2
Description		transmembrane protein 97	programmed cell death 1 ligand 2
Image		No pdb structure
GO Annotations	Cellular Component	Lysosome Endoplasmic Reticulum Rough Endoplasmic Reticulum Plasma Membrane Integral Component Of Membrane Rough Endoplasmic Reticulum Membrane Nuclear Membrane	Extracellular Region Plasma Membrane External Side Of Plasma Membrane Endomembrane System Integral Component Of Membrane
	Molecular Function	Protein Binding	Molecular_function Protein Binding
	Biological Process	Regulation Of Cell Growth Cholesterol Homeostasis	Adaptive Immune Response Immune Response Cell Surface Receptor Signaling Pathway T Cell Costimulation Negative Regulation Of Interferon-gamma Production Negative Regulation Of Interleukin-10 Production Positive Regulation Of T Cell Proliferation Negative Regulation Of T Cell Proliferation Negative Regulation Of Activated T Cell Proliferation Cellular Response To Lipopolysaccharide
Pathways			PD-1 signaling
Drugs
Diseases
GWAS		Advanced age-related macular degeneration ( 26691988) Blood protein levels ( 29875488) Osteoprotegerin levels ( 25080503)	Blood protein levels ( 30072576 29875488 28240269) Serum alkaline phosphatase levels ( 33339817)
Interacting Genes		70 interacting genes: ADCYAP1R1 APP AQP12B AQP2 AQP6 ARL13B ASZ1 ATP6AP2 BCL2L13 BIK CD53 CD74 CGRRF1 CLDN7 CLSTN3 CPLX4 CRLF3 EBP ERAL1 ERGIC3 FAM209A FFAR2 FKBP7 FRMD3 FXYD3 GJB3 GJB5 GPR152 GPR37L1 GPX8 HSD17B13 IFNGR2 KIR2DL3 LEUTX LHFPL5 LIME1 LRRC59 MFF MRM1 MTIF3 MUC1 NDUFAF1 NDUFAF2 NEMP1 ORC1 PDCD1LG2 PDZK1IP1 PLP1 POLDIP2 PSCA REEP1 RHCG RNF167 RNF170 SAR1A SGPL1 SLC14A1 SLC14A2 SPINT1 SSMEM1 TADA1 TBC1D29P TMEM106C TMEM14B TMEM45B TMEM52B TMEM79 TMX2 UTP4 VSIR	21 interacting genes: ATP6V0C ERMP1 EXOSC8 GALNT15 GPR37L1 KTN1 LRP10 MFSD6 PDCD1 RUSF1 SLC35C2 SLC38A1 SLC38A7 SLC41A2 SLC7A1 SMIM3 TAS2R10 TMEM147 TMEM218 TMEM239 TMEM97
Entrez ID		27346	80380
HPRD ID		14343	16147
Ensembl ID		ENSG00000109084	ENSG00000197646
Uniprot IDs		Q5BJF2	Q9BQ51
PDB IDs			6UMT
Enriched GO Terms of Interacting Partners?
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