CNTN6 and CNTN4

		CNTN6	CNTN4
Description		contactin 6	contactin 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Axon Parallel Fiber To Purkinje Cell Synapse Anchored Component Of Presynaptic Membrane	Extracellular Region Plasma Membrane Axon Anchored Component Of Membrane
	Molecular Function	Cell-cell Adhesion Mediator Activity	Cell-cell Adhesion Mediator Activity
	Biological Process	Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Notch Signaling Pathway Axon Guidance Central Nervous System Development Positive Regulation Of Notch Signaling Pathway Dendrite Self-avoidance	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Neuron Cell-cell Adhesion Nervous System Development Axonogenesis Axon Guidance Axonal Fasciculation Brain Development Neuron Projection Development Negative Regulation Of Neuron Differentiation Regulation Of Synaptic Plasticity Dendrite Self-avoidance
Pathways		CHL1 interactions	Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Diseases
GWAS		Depressive symptoms (stressful life events interaction) ( 27529621) Diastolic blood pressure ( 28270201) Disease progression in age-related macular degeneration ( 29346644) Fasting blood insulin ( 29621232) Gut microbiota (bacterial taxa) ( 27723756) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) High density lipoprotein cholesterol levels ( 31647587 34074324) High myopia ( 32428537) Iris color (L* coordinate) ( 30895295) Loneliness ( 27629369) Metabolite levels ( 23823483) Neurocognitive impairment in HIV-1 infection (continuous) ( 28447399) PR interval in Tripanosoma cruzi seropositivity ( 24324551) Response to selenium supplementation (change in plasma selenium concentration) ( 33382417) Response to statin therapy ( 20339536) Systemic lupus erythematosus ( 24871463) Venous thromboembolism ( 23650146) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)	Acenocoumarol maintenance dosage ( 19578179) Amyotrophic lateral sclerosis ( 19451621) Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Atypical femoral fracture in phosphonate treatment ( 31006051) Autism spectrum disorder or schizophrenia ( 28540026) Basophil percentage of granulocytes ( 27863252) Basophil percentage of white cells ( 27863252) Bisphosphonate-associated atypical femoral fracture ( 31006051) Blood pressure ( 17903302) Blood pressure (smoking interaction) ( 25189868) Blood protein levels ( 30072576 29875488) Body mass index (change over time) in chronic obstructive pulmonary disease ( 28044437) Brain connectivity ( 23471985) Chronotype ( 30696823) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Daytime sleep phenotypes ( 27126917) Diisocyanate-induced asthma ( 25918132) Disease progression in age-related macular degeneration ( 29346644) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) HDL cholesterol levels in HIV infection ( 33109212) High density lipoprotein cholesterol levels ( 31647587 34074324) High myopia ( 32428537) Intake of total sugars ( 31005972) Intelligence ( 22449649) Metabolite levels ( 23823483) Middle childhood and early adolescence aggressive behavior ( 26087016) Night sleep phenotypes ( 27126917) Pit-and-Fissure caries ( 24556642) Post bronchodilator FEV1/FVC ratio ( 26634245) Response to aripiprazole in schizophrenia ( 29503163) Restless legs syndrome ( 29029846) Schizophrenia ( 28991256 25056061 29483656 30285260 26198764) Sensorimotor dexterity ( 31596458) Serum immune biomarker levels ( 32066700) Serum uric acid levels ( 24379826) Thiopurine-induced pancreatitis in inflammatory bowel disease ( 29923122) Total ventricular volume ( 21116278) White blood cell count (basophil) ( 27863252)
Interacting Genes		1 interacting genes: CNTN4	7 interacting genes: BARD1 BRCA1 CNTN6 ERAP2 GHRL PRICKLE4 TBCA
Entrez ID		27255	152330
HPRD ID		06242	16239
Ensembl ID		ENSG00000134115	ENSG00000144619
Uniprot IDs		A1LMA8 B4DGV0 Q9UQ52	Q8IWV2
PDB IDs
Enriched GO Terms of Interacting Partners?
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