SIT1 and CSK

  • Number of citations of the paper that reports this interaction (PubMedID 11433379)
  • 13
  • Data Source:
  • HPRD (in vivo)

SIT1

CSK

Description signaling threshold regulating transmembrane adaptor 1 C-terminal Src kinase
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel) ( 23648065)
  • Blood pressure ( 21909110)
  • Blood protein levels ( 30072576)
  • Body mass index and systole blood pressure (pairwise) ( 33619380)
  • Caffeine consumption ( 21490707)
  • Coffee consumption ( 31959922)
  • Diastolic blood pressure ( 26390057 19430479 19430483)
  • Diastolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Diastolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
  • Hypertension ( 31513605)
  • Lung cancer ( 28604730)
  • Lung cancer in ever smokers ( 28604730)
  • Mean arterial pressure ( 27618448)
  • Mean arterial pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
  • Medication use (agents acting on the renin-angiotensin system) ( 31015401)
  • Medication use (beta blocking agents) ( 31015401)
  • Medication use (diuretics) ( 31015401)
  • Myocardial infarction ( 33532862)
  • Offspring birth weight ( 31043758)
  • Serum albumin level ( 29403010)
  • Systemic lupus erythematosus ( 27399966 33272962 26502338 28714469)
  • Systemic lupus erythematosus and Systemic sclerosis ( 23740937)
  • Systemic sclerosis ( 31672989)
  • Systolic blood pressure ( 30578418)
  • Systolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Systolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
Interacting Genes 18 interacting genes: APOL2 BMP10 CDKN2A CLRN2 CSK FYN GRB2 ITM2A LCK MALL PLN PTPN11 SYK TMBIM6 TMEM140 TSPAN33 UPK1B ZAP70 53 interacting genes: ADRB2 ARRB1 CAV1 CD247 CD3E CD44 CDC45 CDH5 CREBBP DAB2 DOK1 DOK2 DOK3 ETFA FGR FHL2 FYN G3BP1 GJA1 GSN HCK HNRNPK ID3 IGF1R INSR KANK4 KHDRBS1 LAIR1 LCK LYN MAPK15 PAG1 PDPK1 PECAM1 PLD2 PRKACA PTK2 PTPN12 PTPN18 PTPN22 PXN RASA1 RB1 RGS16 SDC3 SHC1 SIT1 SRC TGFB1I1 TLR3 UBE2I ZAP70 ZNF212
Entrez ID 27240 1445
HPRD ID 05394 00496
Ensembl ID ENSG00000137078 ENSG00000103653
Uniprot IDs Q9Y3P8 A8K3B6 B2R6Q4 P41240
PDB IDs 1BYG 1CSK 3D7T 3D7U 3EAC 3EAZ
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
Tagcloud (Intersection) ?