GNMT and ZNF337

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GNMT	ZNF337
Description		glycine N-methyltransferase	zinc finger protein 337
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol	Nucleus
	Molecular Function	Protein Binding Folic Acid Binding Glycine Binding Glycine N-methyltransferase Activity Identical Protein Binding S-adenosyl-L-methionine Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding
	Biological Process	Glycogen Metabolic Process Regulation Of Gluconeogenesis Cellular Protein Modification Process Methionine Metabolic Process One-carbon Metabolic Process Methylation S-adenosylhomocysteine Metabolic Process S-adenosylmethionine Metabolic Process Protein Homotetramerization Sarcosine Metabolic Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II
Pathways		Metabolism of ingested SeMet, Sec, MeSec into H2Se Glyoxylate metabolism and glycine degradation	Generic Transcription Pathway
Drugs		Ademetionine Glycine S-adenosyl-L-homocysteine
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Blood protein levels ( 30072576 29875488) LDL cholesterol levels ( 32203549) Plasma homocysteine levels (post-methionine load test) ( 24651765)	Lung function (FEV1) ( 30061609)
Interacting Genes		31 interacting genes: ADAMTSL4 ARR3 ARRB1 CCDC153 COX7B CTNS FRG1 GABRQ GAGE2A HDAC7 HPRT1 KRTAP10-3 KRTAP4-2 NIF3L1 NOTCH2NLA NTAQ1 NUDT18 PLEKHF2 POT1 PRKACA RPSA SDCBP SNRNP200 SRD5A2 STT3B TERF1 TERF2 TERF2IP TINF2 TRIM35 ZNF337	12 interacting genes: ATP5F1C CALCOCO2 CCDC125 CCDC85B COMMD3 GNMT HMBOX1 KRT40 KRTAP10-7 MTUS2 PTGER4 RPGRIP1
Entrez ID		27232	26152
HPRD ID		05970	15779
Ensembl ID		ENSG00000124713	ENSG00000130684
Uniprot IDs		A0A0S2Z5F2 Q14749 V9HW60	A8K5C0 Q6ZUQ0 Q9Y3M9
PDB IDs		1R74 2AZT
Enriched GO Terms of Interacting Partners?
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