NDOR1 and HOXB2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		NDOR1	HOXB2
Description		NADPH dependent diflavin oxidoreductase 1	homeobox B2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Intermediate Filament Cytoskeleton Perinuclear Region Of Cytoplasm	Chromatin Nucleus Nucleoplasm
	Molecular Function	NADPH-hemoprotein Reductase Activity Protein Binding Electron Transfer Activity FMN Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On NAD(P)H, Heme Protein As Acceptor Oxidoreductase Activity, Acting On Iron-sulfur Proteins As Donors, NAD Or NADP As Acceptor Flavin Adenine Dinucleotide Binding NADP Binding NADPH Binding FAD Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Cell Death Iron-sulfur Cluster Assembly Electron Transport Chain Cellular Response To Menadione	Morphogenesis Of An Epithelial Sheet Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Blood Circulation Anterior/posterior Pattern Specification Dorsal/ventral Pattern Formation Rhombomere 3 Development Rhombomere 4 Development Facial Nerve Structural Organization Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Morphogenesis Neural Nucleus Development
Pathways		Cytosolic iron-sulfur cluster assembly	Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31152163) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular hemoglobin concentration ( 32888494 27863252) Mean corpuscular volume ( 32888494 27863252) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252)	Body mass index ( 26426971) Experiencing mood swings ( 29500382) Feeling hurt ( 29500382) Keratoconus ( 33649486) Primary tooth development (number of teeth) ( 20195514)
Interacting Genes		31 interacting genes: C7orf57 CCDC33 CENATAC CIAPIN1 CYCS DLG4 EFHC2 ENOX2 GAS8 GPS2 HOXB2 KIAA0408 LMO2 LMO3 LNX1 MEOX1 MTUS2 NAB2 NLK PMPCA PSMB6 TCF4 TCHP TEPSIN TLE5 UBQLN1 UBQLN2 ZBTB42 ZC2HC1C ZNF620 ZNF774	13 interacting genes: CREBBP DTX2 EP300 MID2 MNDA MORN3 NDOR1 PBX4 RCHY1 RUNX1T1 SOD1 UBASH3B ZNF410
Entrez ID		27158	3212
HPRD ID		10444	00854
Ensembl ID		ENSG00000188566	ENSG00000173917
Uniprot IDs		Q9UHB4	P14652
PDB IDs		4H2D
Enriched GO Terms of Interacting Partners?
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