UQCRQ and JADE2

		UQCRQ	JADE2
Description		ubiquinol-cytochrome c reductase complex III subunit VII	jade family PHD finger 2
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex III	Histone Acetyltransferase Complex Nucleoplasm Extracellular Exosome
	Molecular Function		Protein Binding Transferase Activity Metal Ion Binding
	Biological Process	Mitochondrial Electron Transport, Ubiquinol To Cytochrome C Subthalamus Development Pons Development Cerebellar Purkinje Cell Layer Development Hippocampus Development Thalamus Development Hypothalamus Development Pyramidal Neuron Development Midbrain Development	Protein Ubiquitination Histone H3 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K12 Acetylation Histone H4-K16 Acetylation
Pathways		Respiratory electron transport	HATs acetylate histones
Drugs		2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol 6-Hydroxy-5-undecyl-4,7-benzothiazoledione Azoxystrobin (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE (S)-famoxadone METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE 2-Nonyl-4-quinolinol 1-oxide Ubiquinone Q2
Diseases
GWAS		Asthma ( 31619474)	Adult body size ( 32376654) Age at first birth ( 34211149 27798627) Body mass index ( 28892062) Brain morphology (MOSTest) ( 32665545) Coffee consumption ( 31046077) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Hand grip strength ( 29691431) Household income (MTAG) ( 31844048) Mental health study participation (completed survey) ( 31263887) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494) Multiple sclerosis ( 31604244) Neutrophil count ( 32888494) Platelet distribution width ( 27863252) Smoking cessation ( 33082346) Subcortical volume (MOSTest) ( 32665545) Type 2 diabetes ( 28869590) White blood cell count ( 32888494)
Interacting Genes		5 interacting genes: ERCC6 ERCC8 JADE2 OPTN POLR2M	27 interacting genes: C5orf15 CBX8 CDCA7L CSNK2A1 DDX46 FBXO7 FSTL4 GAS2L2 GORASP2 H3-4 ING4 IRAK1 KLK2 MEAF6 PACSIN1 RAPGEF6 SAR1B SASH1 SH2B2 SMAD5-AS1 TCF7 UQCRQ ZBTB3 ZBTB5 ZCCHC10 ZNF417 ZNF496
Entrez ID		27089	23338
HPRD ID		17941	15124
Ensembl ID		ENSG00000164405	ENSG00000043143
Uniprot IDs		O14949	A0A0C4DFT8 B3KPL2 B4DFY8 G3XAA4 Q9NQC1
PDB IDs		5XTE 5XTH 5XTI
Enriched GO Terms of Interacting Partners?
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