GHITM and PLCE1

		GHITM	PLCE1
Description		growth hormone inducible transmembrane protein	phospholipase C epsilon 1
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Integral Component Of Mitochondrial Inner Membrane Extracellular Exosome	Golgi Membrane Cytosol Plasma Membrane Lamellipodium
	Molecular Function	Molecular_function Protein Binding	Phosphatidylinositol Phospholipase C Activity Phospholipase C Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding Enzyme Binding Small GTPase Binding Metal Ion Binding
	Biological Process	Apoptotic Process Inner Mitochondrial Membrane Organization Negative Regulation Of Release Of Cytochrome C From Mitochondria Positive Regulation Of Mitochondrial ATP Synthesis Coupled Electron Transport	Regulation Of Cell Growth Diacylglycerol Biosynthetic Process Regulation Of Smooth Muscle Contraction Cytoskeleton Organization Epidermal Growth Factor Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Ras Protein Signal Transduction Heart Development Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Lamellipodium Assembly Lipid Catabolic Process Calcium-mediated Signaling Glomerulus Development Positive Regulation Of MAPK Cascade Regulation Of Protein Kinase Activity Regulation Of Ras Protein Signal Transduction Phosphatidylinositol-mediated Signaling Inositol Phosphate-mediated Signaling
Pathways			Synthesis of IP3 and IP4 in the cytosol
Drugs
Diseases
GWAS		Abstraction and mental flexibility ( 31596458) Influenza A (H1N1) infection ( 26379185) Metabolite levels ( 23823483) Mild influenza (H1N1) infection ( 26379185) Refractive error ( 32231278)	Birth weight ( 31043758) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Cataracts ( 34127677) Coronary artery disease ( 29212778) Dengue shock syndrome ( 22001756) Diastolic blood pressure ( 27841878 21909115 27618452) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Esophageal cancer ( 21642993) Esophageal cancer and gastric cancer ( 20729852) Esophageal squamous cell carcinoma ( 25129146) Glaucoma ( 31959993) Glaucoma (primary open-angle) ( 33627673 29891935) Glucose homeostasis traits ( 25524916) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Hypertension ( 31879980 21909115) Lifetime average cigarettes per day in chronic obstructive pulmonary disease ( 21685187) Lymphocyte counts ( 32888494) Mean platelet volume ( 32888494) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (calcium channel blockers) ( 31015401) Migraine ( 27182965 27322543) Monocyte count ( 32888494) Offspring birth weight ( 31043758) Optic cup area ( 31798171) Personality traits in bipolar disorder ( 21368711) Plasma clozapine-norclozapine ratio in treatment-resistant schizophrenia ( 30922102) Platelet reactivity in response to clopidogrel treatment ( 32472697) Plateletcrit ( 32888494 27863252) Pulse pressure ( 27841878 28739976 30578418) Response to (pegylated) interferon in chronic hepatitis B ( 30715261) Sudden cardiac arrest ( 21658281) Systolic blood pressure ( 27841878 21909115 28739976 27618452 30578418) Vertical cup-disc ratio ( 31798171 25241763) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for body mass index ( 28448500) White blood cell count ( 32888494)
Interacting Genes		18 interacting genes: AGTR1 CCR4 CCSER2 DRD2 DYDC1 DYDC2 FAM209A FXYD3 GPR35 GPR37 HTR2C HTR4 JSRP1 KLLN PGRMC2 PLCE1 SLC22A1 TMEM242	6 interacting genes: GHITM HRAS KIT LIMS1 NRAS PPP1R3B
Entrez ID		27069	51196
HPRD ID		17038	07087
Ensembl ID		ENSG00000165678	ENSG00000138193
Uniprot IDs		Q9H3K2	B7ZM61 Q9P212
PDB IDs			2BYE 2BYF 2C5L
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?