RPS6KC1 and PBX2

Number of citations of the paper that reports this interaction (PubMedID 14667819)
36

Data Source:
HPRD (two hybrid)

		RPS6KC1	PBX2
Description		ribosomal protein S6 kinase C1	PBX homeobox 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosome Endosome Early Endosome Membrane	Chromatin Nucleus Transcription Regulator Complex
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Phosphatidylinositol Binding Protein Serine Kinase Activity	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding Protein Binding Transcription Factor Binding
	Biological Process	Protein Phosphorylation Signal Transduction	Eye Development Regulation Of Transcription By RNA Polymerase II Brain Development Animal Organ Morphogenesis Proximal/distal Pattern Formation Embryonic Limb Morphogenesis Positive Regulation Of Transcription By RNA Polymerase II Embryonic Organ Development Neuron Development
Pathways
Drugs
Diseases
GWAS		Breast cancer in childhood cancer survivors ( 29059430) Breast cancer in childhood cancer survivors treated with less than 10 gray radiotherapy ( 29059430) Gut microbiota relative abundance (Ruminococcus belonging to family Erysipelotrichaceae) ( 33208821) Interleukin-6 levels in HIV infection ( 33095540) Refractive error ( 32231278)	Advanced age-related macular degeneration ( 26691988) Anxiety ( 33859377) Asthma ( 21804548 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Clozapine-induced agranulocytosis/granulocytopenia in treatment-resistant schizophrenia ( 26876947) Coronary artery disease ( 33020668) Crohn's disease ( 23266558) Hip circumference adjusted for BMI ( 34021172) Inflammatory bowel disease ( 28067908) Moderate to vigorous physical activity levels ( 29899525) Prostate cancer ( 23535732) Refractive error ( 32231278) Rheumatic heart disease ( 32488134) Ulcerative colitis ( 28067908) Waist-hip index ( 34021172)
Interacting Genes		5 interacting genes: PBX2 PRDX3 SAAL1 SPHK1 VDR	39 interacting genes: BAIAP2 BFSP2 BLOC1S1 BLOC1S5 BRMS1L CARD9 CCDC88B CDCA7L CENPBD1P COPS6 DCTN3 EFHC1 ELP1 FAM90A1 HOXA1 HOXA5 HOXA9 HOXB5 HOXB8 HOXC5 HOXC8 HOXC9 MCRS1 MSC MTREX NEU1 NOTCH4 NUP62 PBX1 PKNOX1 PPFIBP1 RIPPLY2 RPL4 RPS6KC1 SMYD3 UBE2E1 ZCWPW2 ZDHHC7 ZNF587
Entrez ID		26750	5089
HPRD ID		10204	08890
Ensembl ID		ENSG00000136643	ENSG00000204304
Uniprot IDs		A0A087X1U5 F5H7T0 F6RJM5 Q96S38	A0A024RCR3 P40425
PDB IDs
Enriched GO Terms of Interacting Partners?
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