GDI1 and RHOH

Number of citations of the paper that reports this interaction (PubMedID 11809807)
41

Data Source:
HPRD (in vitro)

		GDI1	RHOH
Description		GDP dissociation inhibitor 1	ras homolog family member H
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Cytosol Axon Midbody Protein-containing Complex Neuronal Cell Body Myelin Sheath	Immunological Synapse Cytoplasm Cytoskeleton Plasma Membrane Cell Cortex Cytoplasmic Vesicle Cell Projection
	Molecular Function	GDP-dissociation Inhibitor Activity Rab GDP-dissociation Inhibitor Activity GTPase Activator Activity Protein Binding Small GTPase Binding	GTPase Activity GTPase Inhibitor Activity Protein Binding GTP Binding Kinase Inhibitor Activity Protein Kinase Binding Small GTPase Binding
	Biological Process	Signal Transduction Protein Transport Vesicle-mediated Transport Rab Protein Signal Transduction Positive Regulation Of Axon Extension Negative Regulation Of Axonogenesis Regulation Of Catalytic Activity Response To Calcium Ion Negative Regulation Of Protein Targeting To Membrane	Regulation Of Transcription, DNA-templated Actin Filament Organization Establishment Or Maintenance Of Cell Polarity Motor Neuron Axon Guidance Regulation Of Cell Shape Rac Protein Signal Transduction Cell Projection Assembly T Cell Differentiation Cortical Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization Negative Regulation Of Catalytic Activity Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Engulfment Of Apoptotic Cell Mast Cell Activation Positive Regulation Of T Cell Differentiation Regulation Of Neutrophil Migration
Pathways		RAB GEFs exchange GTP for GDP on RABs	RHOH GTPase cycle
Drugs
Diseases
GWAS			Graves' disease ( 21841780) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Metabolite levels ( 23823483) Multiple sclerosis ( 31604244) Pre-treatment viral load in HIV-1 infection ( 31219150)
Interacting Genes		18 interacting genes: CDC42 EPB41 GNL1 IRAK1 LNX1 OGT PACS1 PSEN1 RAB1B RAB27A RAB3B RAB6A RAB9A RABAC1 RAC2 RHOH TK1 UBQLN4	24 interacting genes: ARHGDIA ARHGDIB ARHGDIG BANP CCNH FAM90A1 GDI1 IQUB ITGB1BP1 KANK2 KCNH2 LRIF1 MBLAC1 MTX2 PLEKHA7 RIPPLY1 SCNM1 SORL1 SUOX TCF19 TGFBR1 TMEM33 UTP14A XPNPEP1
Entrez ID		2664	399
HPRD ID		02114	03616
Ensembl ID		ENSG00000203879	ENSG00000168421
Uniprot IDs		A0A0S2Z3X8 P31150	Q15669 Q6ICP4
PDB IDs
Enriched GO Terms of Interacting Partners?
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