FBXO2 and PFDN6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FBXO2	PFDN6
Description		F-box protein 2	prefoldin subunit 6
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Cytosol Membrane SCF Ubiquitin Ligase Complex Dendritic Spine	Cytoplasm Prefoldin Complex
	Molecular Function	Amyloid-beta Binding Ubiquitin-protein Transferase Activity Protein Binding Carbohydrate Binding Ubiquitin Protein Ligase Activity	Amyloid-beta Binding Protein Binding Unfolded Protein Binding Chaperone Binding
	Biological Process	Cellular Protein Modification Process Proteolysis Glycoprotein Catabolic Process Negative Regulation Of Cell Population Proliferation Protein Ubiquitination Ubiquitin-dependent ERAD Pathway SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Ubiquitination	Protein Folding Chaperone-mediated Protein Complex Assembly Negative Regulation Of Amyloid Fibril Formation
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation	Prefoldin mediated transfer of substrate to CCT/TriC
Drugs
Diseases
GWAS			Autism spectrum disorder or schizophrenia ( 28540026)
Interacting Genes		17 interacting genes: AHSG BACE1 BRAP ECPAS IGH IL6ST ITGB1 PAX4 PFDN6 SKP1 STUB1 UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2L3 VSTM1	13 interacting genes: AIMP2 B4GALT2 CCHCR1 CEBPG CFC1 FBXO2 KANK2 KIFC3 MAGEB4 MBD3 PFDN5 RPRD1B THAP11
Entrez ID		26232	10471
HPRD ID		06171	16135
Ensembl ID		ENSG00000116661	ENSG00000204220
Uniprot IDs		Q9UK22	O15212 Q5STK2
PDB IDs			6NR8 6NR9 6NRB 6NRC 6NRD
Enriched GO Terms of Interacting Partners?
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