PTPN22 and CSK

  • Number of citations of the paper that reports this interaction (PubMedID 9582365)
  • 23
  • Data Source:
  • HPRD (in vitro, in vivo)

PTPN22

CSK

Description protein tyrosine phosphatase non-receptor type 22 C-terminal Src kinase
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Blood pressure ( 21909110)
  • Blood protein levels ( 30072576)
  • Body mass index and systole blood pressure (pairwise) ( 33619380)
  • Caffeine consumption ( 21490707)
  • Coffee consumption ( 31959922)
  • Diastolic blood pressure ( 26390057 19430479 19430483)
  • Diastolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Diastolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
  • Hypertension ( 31513605)
  • Lung cancer ( 28604730)
  • Lung cancer in ever smokers ( 28604730)
  • Mean arterial pressure ( 27618448)
  • Mean arterial pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
  • Medication use (agents acting on the renin-angiotensin system) ( 31015401)
  • Medication use (beta blocking agents) ( 31015401)
  • Medication use (diuretics) ( 31015401)
  • Myocardial infarction ( 33532862)
  • Offspring birth weight ( 31043758)
  • Serum albumin level ( 29403010)
  • Systemic lupus erythematosus ( 27399966 33272962 26502338 28714469)
  • Systemic lupus erythematosus and Systemic sclerosis ( 23740937)
  • Systemic sclerosis ( 31672989)
  • Systolic blood pressure ( 30578418)
  • Systolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Systolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
Interacting Genes 18 interacting genes: CBL CD247 CD3E CLK1 CSK EGFR GRB2 GSTP1 HMGCS2 ING4 LCK NOTCH2 PRKCD SARS1 SRPK2 VAV1 WARS2 ZAP70 53 interacting genes: ADRB2 ARRB1 CAV1 CD247 CD3E CD44 CDC45 CDH5 CREBBP DAB2 DOK1 DOK2 DOK3 ETFA FGR FHL2 FYN G3BP1 GJA1 GSN HCK HNRNPK ID3 IGF1R INSR KANK4 KHDRBS1 LAIR1 LCK LYN MAPK15 PAG1 PDPK1 PECAM1 PLD2 PRKACA PTK2 PTPN12 PTPN18 PTPN22 PXN RASA1 RB1 RGS16 SDC3 SHC1 SIT1 SRC TGFB1I1 TLR3 UBE2I ZAP70 ZNF212
Entrez ID 26191 1445
HPRD ID 06100 00496
Ensembl ID ENSG00000134242 ENSG00000103653
Uniprot IDs B4DZW8 G3K0T4 Q9Y2R2 A8K3B6 B2R6Q4 P41240
PDB IDs 2P6X 2QCJ 2QCT 3BRH 3H2X 3OLR 3OMH 4J51 1BYG 1CSK 3D7T 3D7U 3EAC 3EAZ
Enriched GO Terms of Interacting Partners?
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