MAGI3 and TNK2

  • Number of citations of the paper that reports this interaction (PubMedID 19144635)
  • 30

MAGI3

TNK2

Description membrane associated guanylate kinase, WW and PDZ domain containing 3 tyrosine kinase non receptor 2
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Aging traits (healthspan, parental lifespan or longevity) (multivariate analysis) ( 32678081)
  • Alopecia areata ( 25608926)
  • Autoimmune thyroid disease ( 32581359)
  • Bacteremia ( 27236921)
  • Bulimia nervosa ( 23568457)
  • Cerebrospinal fluid clusterin levels ( 26545630)
  • Cognitive decline rate in late mild cognitive impairment ( 26252872)
  • Crohn's disease ( 28067908)
  • Gut microbiota (bacterial taxa) ( 27694959)
  • Leukocyte telomere length ( 32109421)
  • Lung cancer ( 31577861)
  • Myocardial infarction ( 33532862)
  • Neuroblastoma or malignant cutaneous melanoma ( 31605138)
  • Obesity-related traits ( 23251661)
  • Parental lifespan ( 30642433)
  • Type 1 diabetes and autoimmune thyroid diseases ( 25936594)
Interacting Genes 18 interacting genes: ADGRB1 ADRB1 CRHR1 DSCAML1 FMR1 FZD4 FZD7 GRIN2B LATS1 NRCAM PLXNB3 PRRG4 PTEN PTPRB RPS6KA1 TGFA TNK2 VANGL2 49 interacting genes: AKT1 AQP1 AR ARSL BAG3 CDC42 CLTC CSPG4 CTTN CYSRT1 DPH2 EGFR FGFR1 FYN GALT GRB2 HCK HECW1 HSH2D HSP90AB2P ITFG2 KCNA5 KRTAP10-3 MAGI3 MCF2 MERTK NCK1 NEK6 NOTCH2NLA NPHP1 PDGFRB PIK3R3 RASGEF1C RASGRF1 RPL18A SEZ6 SH2D1A SH2D1B SIAH1 SMURF1 SNX9 SOCS4 SRC SRSF5 VTI1B WAS WWOX WWP2 YES1
Entrez ID 260425 10188
HPRD ID 11290 06104
Ensembl ID ENSG00000081026 ENSG00000061938
Uniprot IDs Q5TCQ9 A0A499FJ16 A0A5F9ZGX5 A0A5F9ZHJ2 B3KXJ4 C9J1X3 Q07912
PDB IDs 3SOE 1CF4 1U46 1U4D 1U54 3EQP 3EQR 4EWH 4HZR 4HZS 4ID7 5ZXB 6VQM
Enriched GO Terms of Interacting Partners?
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