SS18L1 and TCF7

Number of citations of the paper that reports this interaction (PubMedID 20211142)
361

Data Source:
BioGRID (two hybrid)

		SS18L1	TCF7
Description		SS18L1 subunit of BAF chromatin remodeling complex	transcription factor 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Kinetochore Nucleus Nucleoplasm Cytosol Nuclear Body NBAF Complex	Nucleus Nucleoplasm Nuclear Body Beta-catenin-TCF Complex
	Molecular Function	Transcription Coactivator Activity Protein Binding	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity Protein Binding Beta-catenin Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Chromatin Organization Dendrite Development Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Dendrite Morphogenesis	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Immune Response T Cell Receptor V(D)J Recombination Gamma-delta T Cell Differentiation Regulation Of Gamma-delta T Cell Differentiation Negative Regulation Of Transcription, DNA-templated Canonical Wnt Signaling Pathway Cellular Response To Interleukin-4
Pathways			Formation of the beta-catenin:TCF transactivating complex Formation of the beta-catenin:TCF transactivating complex Deactivation of the beta-catenin transactivating complex Ca2+ pathway Binding of TCF/LEF:CTNNB1 to target gene promoters Repression of WNT target genes Repression of WNT target genes RUNX3 regulates WNT signaling
Drugs
Diseases
GWAS		Liver enzyme levels (alkaline phosphatase) ( 33972514)	Autoimmune thyroid disease ( 32581359) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Medication use (thyroid preparations) ( 31015401) Menarche (age at onset) ( 25231870) Multiple sclerosis ( 31604244 24076602 21833088) Rheumatoid arthritis ( 32868391) Sum eosinophil basophil counts ( 27863252) Systemic lupus erythematosus ( 27399966 33272962 26502338 28714469) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		43 interacting genes: AATF ANKRD22 ATF3 ATN1 BAG4 BICRAL BRD1 C1orf94 CEP55 CREBBP CSTF2 DGCR6 ELF5 EP300 FAM168A GATAD1 HDAC2 HDAC4 HGS LGALS3 MAPK1IP1L MED30 MIA2 NAF1 NR1H3 PAX8 PCGF6 RFX6 RLIM SF3B4 SMAD1 SMAD3 SMARCA4 SNRPB SNRPC SSBP3 STAT3 TAF9B TCF7 TNK1 USP54 ZMIZ2 ZMYND19	4 interacting genes: GOLGA3 JADE2 SS18L1 UCHL5
Entrez ID		26039	6932
HPRD ID		09398	01797
Ensembl ID		ENSG00000184402	ENSG00000081059
Uniprot IDs		B4DSR7 O75177	B3KQ75 P36402
PDB IDs
Enriched GO Terms of Interacting Partners?
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