PNKD and MYL12B

Number of citations of the paper that reports this interaction (PubMedID 15188056)
12

Data Source:
HPRD (in vitro, two hybrid)

		PNKD	MYL12B
Description		PNKD metallo-beta-lactamase domain containing	myosin light chain 12B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Membrane	Stress Fiber Cytosol Brush Border Myosin II Complex Z Disc Apical Part Of Cell Extracellular Exosome Cell Cortex Region
	Molecular Function	Hydroxyacylglutathione Hydrolase Activity Protein Binding Metal Ion Binding	Calcium Ion Binding Protein Binding Myosin Heavy Chain Binding
	Biological Process	Methylglyoxal Catabolic Process To D-lactate Via S-lactoyl-glutathione Regulation Of Synaptic Transmission, Dopaminergic Regulation Of Dopamine Metabolic Process Negative Regulation Of Neurotransmitter Secretion Neuromuscular Process Controlling Posture	Regulation Of Cell Shape
Pathways			EPHA-mediated growth cone collapse Sema4D induced cell migration and growth-cone collapse Smooth Muscle Contraction RHO GTPases activate PKNs RHO GTPases activate CIT RHO GTPases Activate ROCKs RHO GTPases activate PAKs RHO GTPases activate PAKs
Drugs
Diseases
GWAS		Colorectal cancer ( 28960316) Colorectal cancer or advanced adenoma ( 30510241) Glycated hemoglobin levels ( 34059833) Granulocyte count ( 27863252) Height ( 28552196) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Hip circumference adjusted for BMI ( 34021172) Immature fraction of reticulocytes ( 32888494) Inflammatory bowel disease ( 28067908 23128233) Liver enzyme levels (alkaline phosphatase) ( 33972514) Monocyte count ( 27863252) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252) Plateletcrit ( 32888494 27863252) Red cell distribution width ( 32888494 27863252 28957414) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Systolic blood pressure ( 30578418) Triglyceride levels ( 32203549) White blood cell count ( 27863252)	Response to methotrexate in juvenile idiopathic arthritis ( 24709693)
Interacting Genes		8 interacting genes: APP CNPPD1 ENO3 GMPPA KCTD9 MAGEA11 MYL12B SPEG	5 interacting genes: DAPK1 HSPB1 MYLIP NSMF PNKD
Entrez ID		25953	103910
HPRD ID		11369	10095
Ensembl ID		ENSG00000127838	ENSG00000118680
Uniprot IDs		A0A024R415 Q8N490	O14950
PDB IDs
Enriched GO Terms of Interacting Partners?
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