ALS2CL and RAB31

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ALS2CL	RAB31
Description		ALS2 C-terminal like	RAB31, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol	Phagocytic Cup Early Endosome Cytosol Plasma Membrane Endomembrane System Secretory Granule Membrane Early Endosome Membrane Trans-Golgi Network Membrane Early Phagosome Membrane Phagocytic Vesicle
	Molecular Function	GTPase Activator Activity Protein Binding Identical Protein Binding	GTPase Activity Protein Binding GTP Binding GDP Binding
	Biological Process	Endosome Organization Regulation Of Catalytic Activity	Intracellular Protein Transport Receptor Internalization Cellular Response To Insulin Stimulus Golgi To Plasma Membrane Protein Transport Regulated Exocytosis Positive Regulation Of Phagocytosis, Engulfment Phagosome Maturation
Pathways		RAB GEFs exchange GTP for GDP on RABs	Neutrophil degranulation RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS			Age at first sexual intercourse ( 27089180) Basophil count ( 32888494) Blood pressure (age interaction) ( 24954895) Bone fracture in osteoporosis ( 28580392) Dupuytren's disease ( 28886342) Lung adenocarcinoma ( 28604730)
Interacting Genes		7 interacting genes: EEF1AKMT3 PPP1R32 RAB22A RAB31 RAB5A RAB5C RSPH14	7 interacting genes: ALS2CL EEA1 EGFR IRAK1 MAPK6 MPP3 OCRL
Entrez ID		259173	11031
HPRD ID		10643	05751
Ensembl ID		ENSG00000178038	ENSG00000168461
Uniprot IDs		A0A024R2U1 Q60I27	Q13636
PDB IDs			2FG5
Enriched GO Terms of Interacting Partners?
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