RAD54B and DMC1

Number of citations of the paper that reports this interaction (PubMedID 15164066)
74

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		RAD54B	DMC1
Description		RAD54 homolog B	DNA meiotic recombinase 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Chromosome, Telomeric Region Condensed Nuclear Chromosome Nucleus Chromosome
	Molecular Function	DNA Binding DNA Helicase Activity RNA Helicase Activity Protein Binding ATP Binding DNA Translocase Activity Hydrolase Activity ATP-dependent Chromatin Remodeler Activity	DNA Strand Exchange Activity DNA Binding Double-stranded DNA Binding Single-stranded DNA Binding Protein Binding ATP Binding ATP-dependent Activity, Acting On DNA Identical Protein Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination Mitotic Recombination Reciprocal Meiotic Recombination Determination Of Adult Lifespan Response To Xenobiotic Stimulus Response To Ionizing Radiation DNA Duplex Unwinding	DNA Recombinase Assembly Ovarian Follicle Development Oocyte Maturation Mitotic Recombination Homologous Chromosome Pairing At Meiosis Reciprocal Meiotic Recombination Male Meiosis I Spermatogenesis Spermatid Development Female Gamete Generation Strand Invasion Meiotic Cell Cycle Chromosome Organization Involved In Meiotic Cell Cycle
Pathways			Meiotic recombination
Drugs			Imidazole
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Nonsyndromic cleft lip with cleft palate ( 28232668)	Gamma glutamyl transferase levels ( 29403010) HDL cholesterol levels ( 32203549) Hematocrit ( 32888494) Menopause (age at onset) ( 26414677) Sleep duration ( 30846698)
Interacting Genes		31 interacting genes: ANKRD36BP1 ATPAF2 BAAT CCDC33 CDC23 CSNK1E DMC1 DYRK2 ELOA ENKD1 GMCL1 GORASP2 IGFBP3 LNX1 MDM4 MYO15B NDUFB9 NIF3L1 NUDT18 PRKAA1 PSMA1 RAD51 RIBC2 SFRP2 SUMO1 TCEANC TRAPPC6A TRMO UBE2I WRN ZNF580	19 interacting genes: BRCA2 C1orf112 FIGNL1 GORASP2 KCTD17 LNX1 MSH4 NIF3L1 PIAS2 PICK1 PSMA3 RAD51 RAD51AP1 RAD54B RPA1 SDCBP SDCBP2 TRIM23 UBE2I
Entrez ID		25788	11144
HPRD ID		05049	04099
Ensembl ID		ENSG00000197275	ENSG00000100206
Uniprot IDs		O95073 Q9Y620	Q14565
PDB IDs			1V5W 2ZJB 4HYY 6R3P 7C98 7C99 7C9C 7CGY
Enriched GO Terms of Interacting Partners?
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