SUN2 and MUC16

		SUN2	MUC16
Description		Sad1 and UNC84 domain containing 2	mucin 16, cell surface associated
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Condensed Nuclear Chromosome Nuclear Envelope Integral Component Of Nuclear Inner Membrane Endosome Membrane Nuclear Membrane Meiotic Nuclear Membrane Microtubule Tethering Complex	Golgi Lumen Plasma Membrane Integral Component Of Membrane Extrinsic Component Of Membrane Vesicle Extracellular Exosome
	Molecular Function	Protein Binding Lamin Binding Microtubule Binding Identical Protein Binding Protein-membrane Adaptor Activity Cytoskeleton-nuclear Membrane Anchor Activity	Protein Binding
	Biological Process	Nuclear Envelope Organization Mitotic Spindle Organization Nuclear Migration Nucleokinesis Involved In Cell Motility In Cerebral Cortex Radial Glia Guided Migration Positive Regulation Of Cell Migration Nuclear Migration Along Microfilament Meiotic Cell Cycle Centrosome Localization Nuclear Matrix Anchoring At Nuclear Membrane	Cell Adhesion
Pathways		Meiotic synapsis	Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) Defective GALNT12 causes colorectal cancer 1 (CRCS1) Dectin-2 family O-linked glycosylation of mucins Termination of O-glycan biosynthesis
Drugs			Oregovomab
Diseases
GWAS		Heel bone mineral density ( 28869591) Prostate cancer ( 31562322) Resting heart rate ( 27798624) Sleep duration ( 30846698)	Asthma ( 30929738 32296059) Hepcidin/transferrin saturation ratio ( 27846281) Serum cancer antigen 125 levels ( 31666285) Tourette syndrome ( 30818990)
Interacting Genes		14 interacting genes: ALS2 APOBEC3C HGS MAFF MUC16 NRM PAEP PSMC2 RAB5B RASD2 RGS2 RPS20 SH3BP1 TXN2	5 interacting genes: LGALS1 MSLN ODAD3 SUN2 UBC
Entrez ID		25777	94025
HPRD ID		15611	07548
Ensembl ID		ENSG00000100242	ENSG00000181143
Uniprot IDs		A0A024R1P7 B4E2A6 Q9UH99	B3KY81 Q8WXI7
PDB IDs		3UNP 4DXR 4DXS 4DXT 4FI9 6WMD 6WME 6WMF 6WMG
Enriched GO Terms of Interacting Partners?
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