GABPB1 and HCFC1

Number of citations of the paper that reports this interaction (PubMedID 10675337)
33

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		GABPB1	HCFC1
Description		GA binding protein transcription factor subunit beta 1	host cell factor C1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasmic Ribonucleoprotein Granule	Histone Acetyltransferase Complex Nucleus Nucleoplasm Cytoplasm Membrane Axon Dendrite Protein-containing Complex Histone Methyltransferase Complex Neuronal Cell Body Set1C/COMPASS Complex MLL1 Complex
	Molecular Function	Transcription Cis-regulatory Region Binding Protein Binding	Chromatin Binding Transcription Coactivator Activity Protein Binding Protein-macromolecule Adaptor Activity Identical Protein Binding Cadherin Binding DNA-binding Transcription Factor Binding
	Biological Process	Mitochondrion Organization Positive Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Remodeling Regulation Of Transcription, DNA-templated Cell Cycle Positive Regulation Of Gene Expression Release From Viral Latency Regulation Of Protein-containing Complex Assembly Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K16 Acetylation Positive Regulation Of Cell Cycle Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Protein Stabilization Cellular Response To Organic Cyclic Compound
Pathways			Transcriptional activation of mitochondrial biogenesis HATs acetylate histones UCH proteinases
Drugs
Diseases
GWAS		Superior frontal gyrus volume ( 31530798)	Celiac disease ( 22057235) Rheumatoid arthritis ( 23143596) Rheumatoid arthritis (ACPA-positive) ( 23143596) Systemic lupus erythematosus ( 26502338)
Interacting Genes		29 interacting genes: ADGRB2 ATF1 BAIAP2L2 CIC FAM90A1 FANCG GABPA HCFC1 IL16 LMO1 LMO3 LMO4 MAGEB18 MED20 POGZ RBM11 RSPH14 RYBP SLC27A2 SNRPA SNRPB2 SNW1 TDRD7 TRAF2 TRIM55 TRIM63 USO1 YAF2 ZDHHC17	34 interacting genes: ASF1B CLP1 CREB3 CREBZF E2F1 E2F3 E2F4 EGR2 FOXK2 GABPA GABPB1 HCFC1R1 HSPA1A JUN KMT2A MED25 NFE2L1 OGT PDCD2 POU2F1 PPARGC1A PPARGC1B PPP1CC PSIP1 SETD7 SIAH1 SIN3A SP1 SUMO2 TAF9 THAP11 THAP7 YY1 ZBTB17
Entrez ID		2553	3054
HPRD ID		15975	02061
Ensembl ID		ENSG00000104064	ENSG00000172534
Uniprot IDs		A0A024R5R5 A0A024R5X6 Q06547	A6NEM2 P51610
PDB IDs			4GO6 4N39 4N3A 4N3B 4N3C 5LWV 6MA1 6MA2 6MA3 6MA4 6MA5
Enriched GO Terms of Interacting Partners?
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