TMEM86B and BCL2L13

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid, two hybrid)

		TMEM86B	BCL2L13
Description		transmembrane protein 86B	BCL2 like 13
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane	Nucleus Mitochondrion Integral Component Of Membrane Mitochondrial Membrane
	Molecular Function	Protein Binding Ether Hydrolase Activity Identical Protein Binding Alkenylglycerophosphocholine Hydrolase Activity Alkenylglycerophosphoethanolamine Hydrolase Activity	Protein Binding Cysteine-type Endopeptidase Activator Activity Involved In Apoptotic Process
	Biological Process	Phosphatidylcholine Acyl-chain Remodeling Ether Lipid Metabolic Process	Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Apoptotic Process
Pathways		Acyl chain remodelling of PC
Drugs
Diseases
GWAS		Mean reticulocyte volume ( 32888494) Phosphatidylethanolamine-ether levels ( 31551469) Serum metabolite levels ( 33031748) Systemic lupus erythematosus ( 33536424 28714469)	Baseline cortisol levels in response to low dose short synacthen test in corticosteroid treated asthma ( 29551627) Eosinophil counts ( 32888494) Granulocyte count ( 27863252) Hemoglobin levels ( 32327693) Interleukin-10 levels ( 22205395) Lymphocyte percentage of white cells ( 32888494) Monocyte count ( 32888494) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494 27863252) Neutrophil percentage of white cells ( 32888494) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 32888494)
Interacting Genes		105 interacting genes: AQP6 ARL13B ARL6IP6 ASGR2 BCL2L13 BIK BMP10 C2CD2L CCDC167 CCDC34 CCL4 CD53 CD79A CLRN1 CYB5B DHRSX DNAJC30 EBP ERGIC3 ERP29 EVI2B F11R FAM209A FAXDC2 FKBP7 FXYD6 GJA1 GJA4 GJA8 GOLM1 GPR37L1 GPX8 GUCA2A HIBADH HSD17B13 IER3IP1 IFITM3 KIR2DL3 LAPTM4B LIME1 LSS LY6D MARCHF2 MFF MGST3 MMGT1 MS4A14 MSMO1 MUC1 NDUFAF1 NEMP1 NINJ2 ORMDL2 OTULINL PEX11G PGRMC2 PIGF PLN PSCA PTPN1 PTPN9 RHBDD1 RHOT2 RPRM RTP2 SEC22B SERINC2 SFRP1 SFT2D1 SFXN5 SLC10A6 SLC29A2 SLC35G2 SLC39A9 SMIM1 SNORC SSMEM1 STOM STX12 STX6 STX8 TEX29 THAP4 THBD TIMM23 TMEM106A TMEM107 TMEM120A TMEM14A TMEM14C TMEM203 TMEM237 TMEM248 TMEM52B TMEM60 TMPRSS2 TMX2 TREX1 TSNARE1 USE1 VAMP2 VAMP3 VAMP5 VAPA ZDHHC22	56 interacting genes: ADIPOQ AGTRAP AIG1 APOD APP AQP1 BET1 C4orf3 CD53 CLDN19 CRB3 DEFB127 ERG28 ERMP1 FAM210B FXYD3 FZD7 GABARAPL2 GALNT2 GAST HMOX2 IL17RA JAGN1 LAT LPAR3 MAL MTNR1B NINJ2 PLLP PLN PLP1 PLPP4 SLC30A8 SLC35A1 SLC35G5 SMIM1 SPOCK1 STX12 STX8 TM6SF2 TMEM128 TMEM14C TMEM242 TMEM254 TMEM51 TMEM72 TMEM86A TMEM86B TMEM97 TMUB2 TNF TNMD TRARG1 UPK1B VAMP3 VAMP4
Entrez ID		255043	23786
HPRD ID		14540	09822
Ensembl ID		ENSG00000180089	ENSG00000099968
Uniprot IDs		Q8N661	A0A087WTL4 A0A087WW80 A0A087WX97 A0A0A0MR90 A8K5Y4 B2RB43 B7Z238 B7Z737 E9PDD6 F6VJB4 Q86T62 Q9BXK5
PDB IDs			2IPD
Enriched GO Terms of Interacting Partners?
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