RALGAPA1 and ATP6V1A

		RALGAPA1	ATP6V1A
Description		Ral GTPase activating protein catalytic subunit alpha 1	ATPase H+ transporting V1 subunit A
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Vacuolar Proton-transporting V-type ATPase, V1 Domain Nucleoplasm Lysosomal Membrane Cytosol Plasma Membrane Microvillus Apical Plasma Membrane Proton-transporting Two-sector ATPase Complex Transport Vesicle Secretory Granule Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	GTPase Activator Activity Protein Heterodimerization Activity	Protein Binding ATP Binding Proton-transporting ATP Synthase Activity, Rotational Mechanism Proton-transporting ATPase Activity, Rotational Mechanism
	Biological Process	Regulation Of Small GTPase Mediated Signal Transduction Activation Of GTPase Activity	Cellular Iron Ion Homeostasis ATP Synthesis Coupled Proton Transport Regulation Of Macroautophagy Cellular Response To Increased Oxygen Levels Proton Transmembrane Transport
Pathways		RHOH GTPase cycle	ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs			Alendronic acid Etidronic acid Tiludronic acid Bafilomycin A1 Bafilomycin B1
Diseases
GWAS		Hematocrit ( 32888494) Hemoglobin ( 32888494) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Liver enzyme levels (alkaline phosphatase) ( 33972514) Monocyte count ( 32888494) Red blood cell count ( 32888494)	Prostate cancer ( 23535732)
Interacting Genes		4 interacting genes: ATP6V1A ERBB3 SRP54 TCF3	15 interacting genes: ANXA7 CD200R1L CDC42 CDKN1A GCH1 GON4L KCNJ9 LPGAT1 LSAMP PPM1D RALGAPA1 SMN1 TK1 TMPRSS7 TUFM
Entrez ID		253959	523
HPRD ID		12324	06120
Ensembl ID		ENSG00000174373	ENSG00000114573
Uniprot IDs		A0A1B0GUI1 Q6GYQ0	P38606
PDB IDs			6WLZ 6WM2 6WM3 6WM4
Enriched GO Terms of Interacting Partners?
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