ZNF620 and METTL21A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ZNF620	METTL21A
Description		zinc finger protein 620	methyltransferase 21A, HSPA lysine
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleoplasm Cytoplasm Cytosol Protein-containing Complex
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding	Protein Binding Protein Methyltransferase Activity Protein-lysine N-methyltransferase Activity Hsp70 Protein Binding Heat Shock Protein Binding ATPase Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II	Protein Methylation Peptidyl-lysine Methylation Regulation Of ATPase Activity
Pathways		Generic Transcription Pathway	Protein methylation
Drugs
Diseases
GWAS		Neuroticism ( 29255261)	HDL cholesterol levels ( 32203549) Opioid sensitivity ( 23183491) Systolic blood pressure ( 28135244 28739976 30578418)
Interacting Genes		72 interacting genes: ABLIM3 ATG9A BFSP2 BOLA2 BOLA2B C1orf216 C22orf39 CABP5 CARD9 CCDC102B CCDC6 CCHCR1 CCNC CDCA7L CDKN2D CHAF1A CIB3 CINP CLIC3 CTNNA3 DGCR6L DTX2 EAF1 EEF2KMT EIF4A2 EPM2AIP1 EXOSC5 FHL2 GAS8 GLYCTK GRB2 GYS1 IGFN1 IL16 JRK KCTD9 LMO1 LMO3 MAGOHB MAP2K5 METTL21A MFAP1 MISP MLX MYOZ3 NDOR1 NME7 NOXA1 OAZ3 PIBF1 PIK3R3 PLOD3 POLE2 RIPPLY1 RUSC1 SAAL1 SART3 SLIT1 SNAPC3 TENT5B TPM2 TRAF4 TRIM10 TRIM50 TSEN15 TSR2 USP20 ZBTB16 ZFHX3 ZIC1 ZNF24 ZNF648	17 interacting genes: ARPC4 ATRIP DNAH7 GIGYF2 HSPA1A HSPA5 HSPA8 LNX1 LZTS1 MEI4 MEOX2 MSRB3 PFDN5 ZBED8 ZNF620 ZNF655 ZRANB1
Entrez ID		253639	151194
HPRD ID		15878	14090
Ensembl ID		ENSG00000177842	ENSG00000144401
Uniprot IDs		Q6ZNG0	C9JES0 H7BXH9 Q8WXB1
PDB IDs			4LEC
Enriched GO Terms of Interacting Partners?
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