GAST and LHFPL2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GAST	LHFPL2
Description		gastrin	LHFPL tetraspan subfamily member 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Cellular_component Plasma Membrane Membrane Integral Component Of Membrane Platelet Alpha Granule Membrane
	Molecular Function	Hormone Activity Protein Binding	Molecular_function Protein Binding
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Response To Food	Single Fertilization Biological_process Development Of Primary Female Sexual Characteristics Development Of Primary Male Sexual Characteristics Positive Regulation Of Fertilization
Pathways		G alpha (q) signalling events Gastrin-CREB signalling pathway via PKC and MAPK	Platelet degranulation
Drugs		Oxetacaine
Diseases
GWAS			Birth weight ( 31043758) Blood and toenail selenium levels ( 25343990) Hippocampal atrophy ( 19668339) Macular thickness ( 30535121) Metabolite levels ( 23823483) Parkinson's disease (familial, age at onset) ( 27402877) Platelet count ( 32888494 27863252) Platelet distribution width ( 32888494 27863252) Plateletcrit ( 32888494 27863252) Pulse pressure ( 28135244 27841878 30578418) Systolic blood pressure ( 27841878 30578418)
Interacting Genes		24 interacting genes: AQP6 AQP9 ASPH BCL2L13 CISD2 CP CPE CREB3L1 CYB5R3 ERGIC3 FAM209A GOLM1 GPR152 KIR2DL3 KRT34 LHFPL2 MEP1B MMD MME MUC1 PDZK1IP1 PLP1 SLC10A1 TMEM52B	11 interacting genes: FXYD6 GAST GJA5 GJB1 GPR152 OLFM4 SCARF1 SNORC TBCA TMEM128 TMEM147
Entrez ID		2520	10184
HPRD ID		00671	17272
Ensembl ID		ENSG00000184502	ENSG00000145685
Uniprot IDs		A0A0E3VY36 P01350	A0A024RAM8 Q6ZUX7
PDB IDs		5WRJ
Enriched GO Terms of Interacting Partners?
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