VGLL2 and TEAD1

Number of citations of the paper that reports this interaction (PubMedID 12376544)
53

Data Source:
HPRD (in vitro, in vivo)

		VGLL2	TEAD1
Description		vestigial like family member 2	TEA domain transcription factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Chromatin Nucleoplasm Transcription Regulator Complex TEAD-YAP Complex
	Molecular Function	Transcription Coactivator Activity Protein Binding Protein C-terminus Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Skeletal Muscle Tissue Development Positive Regulation Of Transcription By RNA Polymerase II	Regulation Of Transcription By RNA Polymerase II Hippo Signaling Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Embryonic Organ Development Protein-containing Complex Assembly Positive Regulation Of Pri-miRNA Transcription By RNA Polymerase II
Pathways			YAP1- and WWTR1 (TAZ)-stimulated gene expression RUNX3 regulates YAP1-mediated transcription EGR2 and SOX10-mediated initiation of Schwann cell myelination
Drugs
Diseases
GWAS		Aspartate aminotransferase levels ( 33547301) Body size at age 10 ( 32376654) Creatine kinase levels ( 29403010) Diastolic blood pressure ( 27841878) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Facial emotion recognition (fearful faces) ( 28608620) Height ( 20881960 31562340) Hip circumference adjusted for BMI ( 34021172) Lung cancer ( 28604730) Night sleep phenotypes ( 27126917) Serum total protein level ( 29403010) Waist circumference adjusted for body mass index ( 34021172) Waist-hip ratio ( 28552196)	Age at first sexual intercourse ( 34211149) Central retinal vein equivalent ( 26567291) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Diisocyanate-induced asthma ( 25918132) Gut microbiota relative abundance (unclassified genus belonging to family Erysipelotrichaceae) ( 33208821) HDL cholesterol levels x loop diuretics use interaction ( 31806883) Heel bone mineral density ( 30598549) Height ( 28552196 20881960 25282103) Hip circumference adjusted for BMI ( 34021172) HOMA-B (corrected for HOMA-IR) ( 30369944) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Neutrophil count ( 32888494) Rheumatic heart disease ( 34106200)
Interacting Genes		3 interacting genes: MEF2C TEAD1 TEAD3	21 interacting genes: BORCS8-MEF2B ENO1 GCAT HLA-DMB INSR MAX MEF2A MEF2C MYH7 NCOA1 SRF TBP TRIM3 UBTD1 VGLL1 VGLL2 VGLL3 VGLL4 WWTR1 YAP1 ZDHHC17
Entrez ID		245806	7003
HPRD ID		18282	01802
Ensembl ID		ENSG00000170162	ENSG00000187079
Uniprot IDs		Q8N8G2	P28347 Q59EF3
PDB IDs			2HZD 3KYS 4RE1 4Z8E 5NNX 6HIL 6IM5 7CMM
Enriched GO Terms of Interacting Partners?
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