ALK and RASA1

ALK

RASA1

Description ALK receptor tyrosine kinase RAS p21 protein activator 1
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adiponectin levels (BMI-adjusted) ( 26299439)
  • Body mass index ( 25673413)
  • Body size at age 10 ( 32376654)
  • Carbamazepine-induced reaction with eosinophilia and systemic symptoms ( 31066027)
  • Carbamazepine-induced serious cutaneous adverse reaction ( 31066027)
  • Dentures ( 31235808)
  • Gestational age at birth (child effect) ( 31194736)
  • Glucose homeostasis traits ( 25524916)
  • Low density lipoprotein cholesterol levels ( 33339817)
  • Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808)
  • Pre-treatment viral load in HIV-1 infection ( 31219150)
  • Simvastatin-induced myopathy ( 31220337)
  • Spontaneous coronary artery dissection ( 32887874)
  • Systolic blood pressure ( 26969751)
  • Total cholesterol levels ( 33339817)
Interacting Genes 28 interacting genes: BIRC6 CLNS1A DLG2 DNMT3A DUSP19 ERBB2 HADHB HMGB1 IKBKG IRS1 JAK3 MDK MSH2 NLRC4 NPM1 PIK3R1 PLCG1 PPM1A PTN PTPRZ1 RASA1 SHC1 SHC3 SMC1A TNFRSF8 TSPAN16 TTC19 ZC3HC1 96 interacting genes: ABL1 AFAP1L2 ALK ANXA6 APC APP AR ARHGAP1 ARHGAP5 AURKA AURKB BBS10 BCL10 BCR BIRC5 BMPR1A BUB1 CASP3 CASP7 CAV2 CD5 CDKN2A CSF1R CSK DCC DLC1 DNAJA3 DOK1 DOK2 DOK4 EGFR EIF1 EPHA2 EPHB2 EPHB3 ERBB2 ERBB3 ERBB4 EZH2 FES FGFR1 G3BP1 GAB1 GMCL1 GRB2 HCK HRAS HSPD1 HTT IGF1R INSR KDR KHDRBS1 KIT LCK LYN MAGI1 MAP4K4 MET MLH3 NCK1 NRAS NTRK1 OLIG1 PAG1 PDE6D PDGFRB PIK3R1 PMS2 PTK2B PTPRC PTPRJ PXN RAB5A RACK1 RAP1A RB1 SERPINA4 SHC1 SLC9A2 SMAD2 SOCS3 SPSB1 SRC STAU1 STK11 SYK SYN1 TRMT2A WWP1 WWP2 XRCC6 YES1 ZAP70 ZNF366 ZNF579
Entrez ID 238 5921
HPRD ID 00104 00745
Ensembl ID ENSG00000171094 ENSG00000145715
Uniprot IDs B6D4Y2 Q9UM73 P20936 Q59GK3
PDB IDs 2KUP 2KUQ 2XB7 2XBA 2XP2 2YFX 2YHV 2YJR 2YJS 2YS5 2YT2 3AOX 3L9P 3LCS 3LCT 4ANL 4ANQ 4ANS 4CCB 4CCU 4CD0 4CLI 4CLJ 4CMO 4CMT 4CMU 4CNH 4CTB 4CTC 4DCE 4FNW 4FNX 4FNY 4FNZ 4FOB 4FOC 4FOD 4JOA 4MKC 4TT7 4Z55 5A9U 5AA8 5AA9 5AAA 5AAB 5AAC 5FTO 5FTQ 5IMX 5IUG 5IUH 5IUI 5KZ0 5VZ5 6AT9 6CDT 6E0R 6EBW 6EDL 6MX8 7JY4 7JYR 7JYS 7JYT 1WER 1WQ1 2GQI 2GSB 2J05 2J06 2M51 4FSS 6PXB 6PXC 6WAX 6WAY
Enriched GO Terms of Interacting Partners?
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