ARHGAP8 and CYGB

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ARHGAP8	CYGB
Description		Rho GTPase activating protein 8	cytoglobin
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol	Cytosol Neuron Projection Neuronal Cell Body
	Molecular Function	GTPase Activator Activity Protein Binding	Catalase Activity Peroxidase Activity Oxygen Carrier Activity Iron Ion Binding Protein Binding Oxygen Binding Heme Binding Fatty Acid Peroxidase Activity
	Biological Process	Signal Transduction Regulation Of Catalytic Activity Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of ERK1 And ERK2 Cascade	Response To Hypoxia Response To Oxidative Stress Negative Regulation Of Fibroblast Migration Oxygen Transport Fatty Acid Oxidation Negative Regulation Of Collagen Biosynthetic Process Cellular Oxidant Detoxification Negative Regulation Of Hepatic Stellate Cell Activation
Pathways		RHOA GTPase cycle	eNOS activation Intracellular oxygen transport
Drugs
Diseases
GWAS		Binge eating behaviour in bipolar disorder ( 29391396) Body mass index ( 28552196) Electroencephalographic traits in alcoholism ( 22554406) Non-alcoholic fatty liver disease activity score in non-alcoholic fatty liver disease ( 31311600) Weight ( 28552196)
Interacting Genes		6 interacting genes: BNIP2 CTTN CYGB RHOA SH3GL1 ZMYND12	11 interacting genes: ARHGAP8 ATP13A2 CD300C DDI1 FAAP100 LRATD1 MZT1 PRR5-ARHGAP8 PRRG4 TBC1D16 WBP11
Entrez ID		23779	114757
HPRD ID		06448	06479
Ensembl ID		ENSG00000241484	ENSG00000161544
Uniprot IDs		P85298 Q6PJW1	A0A1K0FUB6 Q8WWM9
PDB IDs			1UMO 1URV 1URY 1UT0 1UX9 1V5H 2DC3 3AG0 4B3W
Enriched GO Terms of Interacting Partners?
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