SH3BP4 and MPHOSPH8

Number of citations of the paper that reports this interaction (PubMedID 18654987)
21

Data Source:
BioGRID (two hybrid)

		SH3BP4	MPHOSPH8
Description		SH3 domain binding protein 4	M-phase phosphoprotein 8
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Clathrin-coated Pit Clathrin-coated Vesicle Extracellular Exosome	Nucleosome Heterochromatin Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Plasma Membrane
	Molecular Function	GDP-dissociation Inhibitor Activity Protein Binding Small GTPase Binding Identical Protein Binding	Chromatin Binding Protein Binding Methylated Histone Binding
	Biological Process	Endocytosis Negative Regulation Of Cell Population Proliferation Positive Regulation Of Autophagy Negative Regulation Of Cell Growth Negative Regulation Of TOR Signaling Negative Regulation Of GTPase Activity Amino Acid Import Regulation Of Catalytic Activity Protein Localization To Lysosome Cellular Response To Amino Acid Stimulus	Regulation Of DNA Methylation Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Negative Regulation Of Transcription, DNA-templated Positive Regulation Of DNA Methylation-dependent Heterochromatin Assembly
Pathways		Amino acids regulate mTORC1
Drugs
Diseases
GWAS		Depression in smokers ( 30219690) Dialysis-related mortality ( 21546767) Mean corpuscular hemoglobin ( 29403010) Mean corpuscular volume ( 29403010) Obstetric antiphospholipid syndrome ( 28424481) Orofacial clefts ( 22419666) Platelet count ( 32888494) Plateletcrit ( 32888494) Schizophrenia ( 34099189) Schizophrenia x sex interaction ( 34099189) Triglyceride levels in HIV infection ( 33109212)	Colorectal cancer ( 34062886)
Interacting Genes		23 interacting genes: AMT C2orf73 CCT3 CEP78 CIZ1 DNAJA4 FKBP4 GAPDHS GIPC1 GKAP1 HSPA5 MPHOSPH8 MRGBP NFU1 PLEKHA1 PRR14 PSMA1 TCP1 TTC1 TXNL1 YWHAE YWHAG ZBTB37	5 interacting genes: H3C1 MTRNR2L1 RANBP9 SH3BP4 SIRT1
Entrez ID		23677	54737
HPRD ID		09285	13682
Ensembl ID		ENSG00000130147	ENSG00000196199
Uniprot IDs		Q9P0V3	Q99549
PDB IDs			3LWE 3QO2 3R93 3SVM 6V2S
Enriched GO Terms of Interacting Partners?
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