LSM5 and LSM6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)
HPRD (in vitro)

		LSM5	LSM6
Description		LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated	LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated
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GO Annotations	Cellular Component	Nucleus Nucleoplasm U6 SnRNP Cytoplasm Cytosol U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Lsm2-8 Complex Lsm1-7-Pat1 Complex	P-body Nucleus Nucleoplasm U6 SnRNP Nucleolus Sno(s)RNA-containing Ribonucleoprotein Complex Cytoplasm Cytosol Small Nuclear Ribonucleoprotein Complex U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Lsm2-8 Complex
	Molecular Function	RNA Binding Protein Binding Protein Heterodimerization Activity	RNA Binding Protein Binding Protein Heterodimerization Activity
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing MRNA Catabolic Process Response To Bacterium	MRNA Splicing, Via Spliceosome MRNA Catabolic Process TRNA Processing RNA Splicing Maturation Of SSU-rRNA
Pathways		mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease mRNA Splicing - Major Pathway	mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease mRNA Splicing - Major Pathway
Drugs			Uridine Uridine monophosphate Citric acid
Diseases
GWAS		Body mass index ( 26426971) Extremely high intelligence ( 29520040) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Morning person ( 30696823) Palmitic acid (16:0) levels ( 23362303) Smooth-surface caries ( 24556642)	Malaria ( 31844061) Systolic blood pressure response to hydrochlorothiazide in hypertension ( 27802415)
Interacting Genes		16 interacting genes: DDIT4L EXOSC5 HNRNPD LSM1 LSM2 LSM3 LSM6 LSM7 LSM8 PLK3 SMN1 SNRPE SNRPF TBPL1 TCL1B TEX43	16 interacting genes: APP CLNS1A LSM1 LSM2 LSM3 LSM5 LSM7 LSM8 MCRS1 PATL1 POLD2 SDCBP SMN1 SNRPD2 SNRPF TARDBP
Entrez ID		23658	11157
HPRD ID		06285	06286
Ensembl ID		ENSG00000106355	ENSG00000164167
Uniprot IDs		A0A090N8Y5 Q9Y4Y9	P62312
PDB IDs		3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9 7ABG	3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9 7ABG
Enriched GO Terms of Interacting Partners?
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