PLD3 and CIC

		PLD3	CIC
Description		phospholipase D family member 3	capicua transcriptional repressor
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Lysosomal Membrane Endoplasmic Reticulum Membrane Integral Component Of Membrane Early Endosome Membrane Late Endosome Membrane Lysosomal Lumen Extracellular Exosome	Chromatin Nucleus Nucleoplasm Intracellular Membrane-bounded Organelle
	Molecular Function	Phospholipase D Activity Protein Binding Single-stranded DNA 5'-3' Exodeoxyribonuclease Activity	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding
	Biological Process	Immune System Process DNA Metabolic Process Inflammatory Response Myotube Differentiation Nucleic Acid Phosphodiester Bond Hydrolysis Regulation Of Cytokine Production Involved In Inflammatory Response	Regulation Of Transcription By RNA Polymerase II Brain Development Learning Memory Social Behavior Negative Regulation Of Transcription, DNA-templated
Pathways		Synthesis of PG Role of phospholipids in phagocytosis
Drugs
Diseases
GWAS		Otitis media ( 27632927) Otitis media (chronic) ( 27632927) Otitis media (recurrent) ( 27632927)	Bitter alcoholic beverage consumption ( 31046077) Neutrophil count ( 32888494)
Interacting Genes		16 interacting genes: ANXA7 ATG16L1 BCL2L1 CIC CNIH3 GPR35 HGS NFKB1 OGT OPRM1 SMCO4 SOX4 SPP1 STK11 TK1 VRK2	14 interacting genes: ATXN1 CENPJ CSNK2B GABPB1 GOLGA2 GTPBP3 NFYC PICK1 PLD3 POLR1H PYCR2 SEC62 SETD2 TRIM22
Entrez ID		23646	23152
HPRD ID		07148	10831
Ensembl ID		ENSG00000105223	ENSG00000079432
Uniprot IDs		A0A024R0Q4 Q8IV08	A0A0A0MQR4 Q96RK0
PDB IDs			2M41 4J2J 4J2L 6JRP 6KZG 6KZH
Enriched GO Terms of Interacting Partners?
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