KPNA6 and NOP2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		KPNA6	NOP2
Description		karyopherin subunit alpha 6	NOP2 nucleolar protein
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Membrane Host Cell	Nucleoplasm Nucleolus
	Molecular Function	Protein Binding Nuclear Localization Sequence Binding Nuclear Import Signal Receptor Activity	RNA Binding Protein Binding RRNA (cytosine-C5-)-methyltransferase Activity
	Biological Process	NLS-bearing Protein Import Into Nucleus Viral Genome Replication Positive Regulation Of Transcription By RNA Polymerase II Maternal Process Involved In Female Pregnancy Entry Of Viral Genome Into Host Nucleus Through Nuclear Pore Complex Via Importin Positive Regulation Of Cytokine Production Involved In Inflammatory Response Positive Regulation Of Viral Life Cycle	Ribosomal Large Subunit Assembly Maturation Of LSU-rRNA RNA Methylation Positive Regulation Of Cell Population Proliferation RRNA Base Methylation Regulation Of Signal Transduction By P53 Class Mediator
Pathways			rRNA modification in the nucleus and cytosol TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation
Drugs
Diseases
GWAS		Body mass index ( 26426971)
Interacting Genes		38 interacting genes: ANKRD11 ANP32A ANP32B ARNT BRCA1 CDKN1B CREBBP CSE1L DCPS EPAS1 FAM90A1 FRG1BP GEMIN2 HIF1A IL1A JRK KAT5 KEAP1 KPNB1 LMNA LMNB1 MAGED1 NMNAT1 NOP2 NUP50 OGT POLR3C POM121 POU6F2 RAC1 RELB RNMT SKP2 SMARCB1 STAT1 STAT3 TAF9 ZNF131	11 interacting genes: CDC42 CDCA7L CEP70 KPNA6 MCRS1 MT1F NPM1 PTPRJ SUMO2 UBE2I VPS52
Entrez ID		23633	4839
HPRD ID		09465	01244
Ensembl ID		ENSG00000025800	ENSG00000111641
Uniprot IDs		O60684	P46087
PDB IDs		4UAD
Enriched GO Terms of Interacting Partners?
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