MKRN1 and SLC13A1

Number of citations of the paper that reports this interaction (PubMedID 18407958)
29

Data Source:
BioGRID (protein complementation assay)

		MKRN1	SLC13A1
Description		makorin ring finger protein 1	solute carrier family 13 member 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component Cytosol	Plasma Membrane Integral Component Of Membrane
	Molecular Function	RNA Binding Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Sodium:sulfate Symporter Activity
	Biological Process	Protein Polyubiquitination Protein Ubiquitination	Sodium Ion Transport Sulfate Transport Anion Transmembrane Transport Sulfate Transmembrane Transport
Pathways		AKT phosphorylates targets in the cytosol Regulation of PTEN stability and activity Antigen processing: Ubiquitination & Proteasome degradation	Sodium-coupled sulphate, di- and tri-carboxylate transporters
Drugs
Diseases
GWAS		Age at first birth ( 34211149) Age at first sexual intercourse ( 34211149) General risk tolerance (MTAG) ( 30643258) Gut microbiota relative abundance (unassigned genus belonging to family Lachnospiraceae) ( 33208821) Immature fraction of reticulocytes ( 32888494) Number of sexual partners ( 30643258)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel) ( 23648065) High density lipoprotein cholesterol levels ( 30498476) Systolic blood pressure ( 30578418)
Interacting Genes		26 interacting genes: APC ASH2L BYSL CSNK1G1 DAXX DUSP23 EXOSC8 FADD FAM161A MAP1LC3B MTURN NAA10 OTUB2 PABPC1 RAD23A RAD23B RPS10 SDCBP SLC13A1 TSC2 UBASH3A UBE2D1 UBE2D3 UBE2D4 UBE2W YOD1	31 interacting genes: ACOT2 ACTR10 APLP2 ARL6IP1 ASS1 CD59 COQ5 COQ9 CRYAB DYNLL1 FTL GRN HSPA1A MKRN1 NDUFS5 OGDHL PDZK1 PNPLA6 PRSS8 RHOA SDHD SEC61A1 SELPLG SERPINA1 SLC9A3R1 SLC9A3R2 TBRG1 TM4SF1 TMED10 TP53I11 TSPAN3
Entrez ID		23608	6561
HPRD ID		09673	08394
Ensembl ID		ENSG00000133606	ENSG00000081800
Uniprot IDs		Q9UHC7	A4D0X1 Q2NKK0 Q9BZW2
PDB IDs
Enriched GO Terms of Interacting Partners?
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