DDAH2 and SCGN

Number of citations of the paper that reports this interaction (PubMedID 21528130)
21

Data Source:
BioGRID (pull down)

		DDAH2	SCGN
Description		dimethylarginine dimethylaminohydrolase 2	secretagogin, EF-hand calcium binding protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Cytosol Extracellular Exosome	Extracellular Region Nucleus Cytoplasm Cytosol Dendrite Transport Vesicle Membrane Neuron Projection Terminal Bouton Synapse
	Molecular Function	Catalytic Activity Protein Binding Dimethylargininase Activity Amino Acid Binding	Calcium Ion Binding Protein Binding
	Biological Process	Citrulline Metabolic Process Arginine Metabolic Process Arginine Catabolic Process Nitric Oxide Biosynthetic Process Nitric Oxide Mediated Signal Transduction Negative Regulation Of Apoptotic Process Positive Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Nitric-oxide Synthase Activity	Biological_process Regulation Of Cytosolic Calcium Ion Concentration Regulation Of Presynaptic Cytosolic Calcium Ion Concentration Regulation Of Long-term Synaptic Potentiation
Pathways		eNOS activation
Drugs		Citrulline
Diseases
GWAS		Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Inflammatory bowel disease ( 28067908) Malaria ( 31844061) Ulcerative colitis ( 28067908)	Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Feeling guilty ( 29500382) Fish- and plant-related diet ( 32066663) HDL cholesterol levels ( 32203549) Intrinsic epigenetic age acceleration ( 29374233) Iron status biomarkers ( 19084217) Iron status biomarkers (iron levels) ( 28334935) Iron status biomarkers (total iron binding capacity) ( 28334935) Iron status biomarkers (transferrin saturation) ( 28334935) Liver iron content ( 34128465) Lung cancer in ever smokers ( 28604730) Oily fish consumption ( 32066663) Peak cortisol response to low dose short synacthen test in corticosteroid treated asthma ( 29551627) Plateletcrit ( 32888494) Pork consumption ( 32066663) Refractive error ( 32231278) Squamous cell lung carcinoma ( 28604730) Subcortical volume (MOSTest) ( 32665545) Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Uric acid levels ( 19503597) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		28 interacting genes: ACTN3 ANXA7 ATP1B1 CDC73 CDK4 CDKN1A DNAJB11 FANCL GADD45G IGFN1 MAP3K20 MKNK1 NOXA1 PIN1 PRKAB2 RAP1B RCC1 RPS6KA1 RPS6KA5 SCGN SMN1 STK3 TAF1D TK1 TNFSF11 TRIP13 TSC22D1 VAC14	10 interacting genes: ABI2 ARFGAP2 ATP5F1A CROCC DDAH2 DOC2A KIF5B MLF2 SNAP23 TUBB3
Entrez ID		23564	10590
HPRD ID		09204	10211
Ensembl ID		ENSG00000213722	ENSG00000079689
Uniprot IDs		O95865 V9HW53	O76038
PDB IDs
Enriched GO Terms of Interacting Partners?
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