EXOSC2 and ST6GALNAC1

Number of citations of the paper that reports this interaction (PubMedID 15231747)
57

Data Source:
BioGRID (two hybrid)

		EXOSC2	ST6GALNAC1
Description		exosome component 2	ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Exosome (RNase Complex) Cytoplasmic Exosome (RNase Complex) Exosome (RNase Complex) Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol	Golgi Membrane Integral Component Of Membrane
	Molecular Function	3'-5'-exoribonuclease Activity RNA Binding Exoribonuclease Activity Protein Binding 7S RNA Binding	Alpha-N-acetylgalactosaminide Alpha-2,6-sialyltransferase Activity Sialyltransferase Activity
	Biological Process	Exonucleolytic Trimming To Generate Mature 3'-end Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) RRNA Processing Positive Regulation Of Cell Growth Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic, 3'-5' U4 SnRNA 3'-end Processing Exonucleolytic Catabolism Of Deadenylated MRNA CUT Catabolic Process Nuclear Polyadenylation-dependent RRNA Catabolic Process Nuclear Polyadenylation-dependent TRNA Catabolic Process Nuclear Retention Of Pre-mRNA With Aberrant 3'-ends At The Site Of Transcription Polyadenylation-dependent SnoRNA 3'-end Processing	Protein Glycosylation Oligosaccharide Biosynthetic Process Sialylation
Pathways		ATF4 activates genes in response to endoplasmic reticulum stress mRNA decay by 3' to 5' exoribonuclease Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA KSRP (KHSRP) binds and destabilizes mRNA Major pathway of rRNA processing in the nucleolus and cytosol	Sialic acid metabolism
Drugs
Diseases
GWAS
Interacting Genes		29 interacting genes: ADAMTS13 AMBP ANGPTL2 CACFD1 COLEC12 DIS3 EXOSC4 EXOSC5 EXOSC6 EXOSC7 EXOSC8 EXOSC9 FBXW2 GALNT13 KHSRP KIFBP MRPL48 MTREX MTX2 NCS1 NELFB PALS2 PTEN RNF8 SBK3 ST6GALNAC1 UPF1 VCAM1 ZNF408	2 interacting genes: EXOSC2 NDST1
Entrez ID		23404	55808
HPRD ID		03758	15340
Ensembl ID		ENSG00000130713	ENSG00000070526
Uniprot IDs		B3KQW2 Q13868	Q9NSC7
PDB IDs		2NN6 6D6Q 6D6R 6H25
Enriched GO Terms of Interacting Partners?
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