PUM2 and DAZL

Number of citations of the paper that reports this interaction (PubMedID 12511597)
69

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		PUM2	DAZL
Description		pumilio RNA binding family member 2	deleted in azoospermia like
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoplasmic Stress Granule Nuclear Membrane Perinuclear Region Of Cytoplasm	Nucleus Cytoplasm Protein-containing Complex
	Molecular Function	RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding MiRNA Binding	RNA Binding MRNA 3'-UTR Binding Protein Binding Translation Activator Activity
	Biological Process	Regulation Of Translation Posttranscriptional Regulation Of Gene Expression Stress Granule Assembly Production Of MiRNAs Involved In Gene Silencing By MiRNA Regulation Of MRNA Stability Regulation Of Chromosome Segregation Regulation Of Gene Silencing By MiRNA Positive Regulation Of RIG-I Signaling Pathway Positive Regulation Of Gene Silencing By MiRNA	Germ Cell Development Spermatogenesis Positive Regulation Of Translational Initiation 3'-UTR-mediated MRNA Stabilization
Pathways		Neddylation
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Apolipoprotein B levels ( 32203549) Body mass index ( 28892062) Low density lipoprotein cholesterol levels ( 32154731)	Feeling fed-up ( 29500382) Intelligence ( 28530673) Lung cancer ( 28604730) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917) Smoking initiation ( 33082346) Testicular germ cell tumor ( 25877299 28604728 28604732 23666240)
Interacting Genes		24 interacting genes: AURKA DAZ1 DAZ3 DAZ4 DAZL MED23 MED4 MIR128-2 MIR17 MIR199A1 MIR199A2 MIR214 MIR221 MIR7-1 MIR92A2 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G NANOS1	5 interacting genes: DAZ1 DAZ4 DAZAP1 DAZAP2 PUM2
Entrez ID		23369	1618
HPRD ID		09527	09029
Ensembl ID		ENSG00000055917	ENSG00000092345
Uniprot IDs		B7ZL34 Q8TB72	A0A140VK77 Q92904
PDB IDs		3Q0Q 3Q0R 3Q0S
Enriched GO Terms of Interacting Partners?
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