PPP1R13B and PRPH

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid, proximity labelling technology)

		PPP1R13B	PRPH
Description		protein phosphatase 1 regulatory subunit 13B	peripherin
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Perinuclear Region Of Cytoplasm	Cytoplasm Intermediate Filament Membrane Axon Perikaryon Type III Intermediate Filament Extracellular Exosome
	Molecular Function	P53 Binding Protein Binding	Structural Molecule Activity Protein Binding
	Biological Process	Negative Regulation Of Cell Cycle Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Positive Regulation Of Neuron Death	Intermediate Filament Cytoskeleton Organization
Pathways		Activation of PUMA and translocation to mitochondria TP53 Regulates Transcription of Genes Involved in Cytochrome C Release TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain TP53 Regulates Transcription of Death Receptors and Ligands Regulation of TP53 Activity through Association with Co-factors
Drugs
Diseases
GWAS		Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Bitter alcoholic beverage consumption ( 31046077) Body mass index ( 26426971) General risk tolerance (MTAG) ( 30643258) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656) Triglycerides ( 30275531)	Prostate cancer ( 21743467) Sural nerve amplitude potential ( 30992453)
Interacting Genes		72 interacting genes: ACSF3 APC ARHGAP45 BFSP2 BRCA1 C2orf42 CAPN7 CBY2 CCDC102B CCDC184 CCHCR1 CDC5L CEP57 CEP63 CGN CKS1B DEUP1 DGCR6L DIRAS1 DTNB FAM184A FAM90A1 GAS2L2 GINS4 GOLGA1 HMG20B HNRNPUL1 KHDRBS1 KHDRBS3 KIF9 KIFC3 KRT20 KRT4 LMNB1 LMNB2 LMO1 LMO3 LNX1 MATN4 MCRS1 MIPOL1 MIS18A MLH1 NAP1L2 NDC80 NEK7 NHSL2 PLEKHA5 PPFIA3 PPP1CA PPP1R18 PRKAB2 PRPH PRR35 RALBP1 RASAL3 RASSF8 SALL1 SOGA1 TCL1A TEKT4 TEX12 TEX9 TNIK TP63 TP73 TRAF1 TSG101 TSGA10 TXLNA ZGPAT ZZZ3	36 interacting genes: CDC37 CT55 DDX6 DES FCHO1 INCA1 KIFC3 KRT14 KRT15 KRT16 KRT20 KRT24 KRT27 KRT31 KRT6A KRT75 LCA5L LENG1 LMNB1 LNX1 MAGOHB MYO5A NXF1 PIAS2 PPP1R13B PPP1R18 PRKAA2 PRPH2 PSMA1 TCEA2 TCP10L TTC23 VIM ZC4H2 ZMAT2 ZNF572
Entrez ID		23368	5630
HPRD ID		07345	01365
Ensembl ID		ENSG00000088808	ENSG00000135406
Uniprot IDs		Q96KQ4	B3KWQ6 P41219
PDB IDs		6HL5
Enriched GO Terms of Interacting Partners?
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