FN1 and COL4A2

  • Number of citations of the paper that reports this interaction (PubMedID 3997552)
  • 9
  • Data Source:
  • HPRD (in vivo)

FN1

COL4A2

Description fibronectin 1 collagen type IV alpha 2 chain
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alanine aminotransferase levels ( 33547301)
  • Apolipoprotein B levels ( 32203549)
  • Arterial stiffness ( 31070453)
  • Arterial stiffness index ( 31235810)
  • Blood urea nitrogen levels ( 31152163)
  • Body shape index ( 34021172)
  • Coronary artery calcification ( 22144573)
  • Coronary artery disease ( 32469254 29212778 24262325 26343387 33020668)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • Coronary heart disease ( 21378990)
  • Diastolic blood pressure ( 27841878)
  • Fasting insulin ( 34059833)
  • Glomerular filtration rate ( 29403010)
  • Intake of sweets ( 31005972)
  • Ischemic stroke (small-vessel) ( 29531354)
  • LDL cholesterol ( 30275531)
  • LDL cholesterol levels ( 32203549)
  • Low density lipoprotein cholesterol levels ( 32154731)
  • Maximum retinal arteriolar tortuosity ( 31597446)
  • Middle temporal gyrus volume ( 31530798)
  • Monocyte count ( 32888494)
  • Myocardial infarction ( 26343387)
  • Night sleep phenotypes ( 27126917)
  • Non-lobar intracerebral hemorrhage ( 31430377)
  • Non-lobar intracerebral hemorrhage (MTAG) ( 31430377)
  • Periventricular white matter hyperintensities ( 32517579)
  • Platelet count ( 32888494)
  • Plateletcrit ( 32888494)
  • Retinal arteriolar tortuosity ( 31597446)
  • Septic shock (28-day mortality) ( 32755526)
  • Serum alkaline phosphatase levels ( 33547301)
  • Serum bilirubin levels x sex interaction in metabolic syndrome ( 30621171)
  • Total cholesterol levels ( 30275531)
  • Triglyceride levels ( 32203549)
  • Waist-hip index ( 34021172)
  • Waist-to-hip ratio adjusted for BMI ( 34021172)
  • White matter hyperintensities ( 32358547)
  • White matter hyperintensity burden ( 25663218)
  • White matter hyperintensity volume ( 33293549)
  • White matter hyperintensity volume (adjusted for hypertension) ( 33293549)
  • White matter hyperintensity volume x hypertension interaction (2df) ( 33293549)
Interacting Genes 108 interacting genes: ADAMTS4 AMBP ANOS1 APCS ATXN10 ATXN7 C1QA CCN3 CD44 CDKN2A COL13A1 COL1A1 COL1A2 COL2A1 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 COL6A2 COL7A1 COMP CRP CTSD CXCL12 DCN DUSP10 EGFR F13A1 FAM86B3P FASLG FBLN1 FBLN2 FST FSTL3 GALNT6 GRB2 GSN HGF HOXA1 HRG HSP90AA1 HSPG2 IGFBP3 IGFBP5 ITGA2B ITGA3 ITGA4 ITGA5 ITGA8 ITGB1 ITGB3 ITGB6 ITGB7 KLK3 KPNA2 LACRT LGALS3BP LPA LRG1 LTBP1 MAG MATN2 MEP1A MEP1B MIA MMP9 MTDH MTNR1A MYOC NPTX1 NR0B2 NT5E PELI2 PKD1 PLAT PLG PRELP PRPF40A RARA RBL1 REG3A RPS6KA5 SCGB1A1 SDC2 SGCA SH3GLB1 SKIL SMAD4 SMAD9 SPARC STAT5A TAB1 TAB2 TAC1 TGFBI TGM2 THBS1 TIMD4 TMPRSS6 TNC TNFRSF11B TSHR TTN UBQLN1 VEGFA VHL 24 interacting genes: ANTXR2 ANXA7 APP ATF7IP BGN BMP3 CD93 COL4A1 CSNK2B DAZAP2 FBLN2 FN1 HABP2 MATN2 MMP9 OSM SAA1 SERPINE2 SKIL SMN1 TENT5A TGFBI TK1 VHL
Entrez ID 2335 1284
HPRD ID 00626 00355
Ensembl ID ENSG00000115414 ENSG00000134871
Uniprot IDs B7ZLE5 P02751 Q6MZF4 Q6MZM7 Q6N084 Q9UQS6 A0A024RDW8 P08572
PDB IDs 1E88 1E8B 1FBR 1FNA 1FNF 1FNH 1J8K 1O9A 1OWW 1Q38 1QGB 1QO6 1TTF 1TTG 2CG6 2CG7 2CK2 2CKU 2EC3 2FN2 2FNB 2GEE 2H41 2H45 2HA1 2MNU 2N1K 2OCF 2RKY 2RKZ 2RL0 3CAL 3EJH 3GXE 3M7P 3MQL 3R8Q 3T1W 3ZRZ 4GH7 4JE4 4JEG 4LXO 4MMX 4MMY 4MMZ 4PZ5 5DC0 5DC4 5DC9 5DFT 5J6Z 5J7C 5M0A 5N47 5N48 6HNF 6MFA 6MSV 6NAJ 1LI1 5NAX 5NB2 6MPX
Enriched GO Terms of Interacting Partners?
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