FMO1 and LEPROTL1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FMO1	LEPROTL1
Description		flavin containing dimethylaniline monoxygenase 1	leptin receptor overlapping transcript like 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Integral Component Of Membrane	Endosome Integral Component Of Membrane
	Molecular Function	Monooxygenase Activity N,N-dimethylaniline Monooxygenase Activity Protein Binding Flavin Adenine Dinucleotide Binding NADP Binding	Protein Binding Identical Protein Binding
	Biological Process	Organic Acid Metabolic Process Xenobiotic Metabolic Process Response To Osmotic Stress Toxin Metabolic Process Response To Lipopolysaccharide NADPH Oxidation	Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Negative Regulation Of Growth Hormone Receptor Signaling Pathway
Pathways		FMO oxidises nucleophiles
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Sudden cardiac arrest ( 21658281) Type 2 diabetes (age of onset) ( 28060188)
Interacting Genes		7 interacting genes: CREB3 FLT3 GRINA LEPROTL1 MFSD14B REEP4 SLC10A6	74 interacting genes: AGPAT4 ARL13B CD300C CD79A CISD2 CLDN7 CLEC2D CREB3L1 CYP4F2 EDA EHHADH ELOVL4 EMP1 FCER1G FFAR2 FMO1 GJA5 GJA8 GPR152 GPR42 GPX8 JPH1 KCNJ6 KLRG1 LMBR1 LMNA LNX1 LPAR3 LRRC4C MALL MFSD14B MSR1 NAT8 ORMDL3 PAQR8 PDZK1IP1 PEX16 PLP1 PPP3CC RBFA REEP4 REEP6 RNF5 RTP2 SCN3B SDCBP SFXN3 SLC16A2 SLC25A46 SLC30A4 SLC35C2 SLC7A1 SMCO4 SPG21 SSMEM1 STING1 STX12 SYNDIG1 TGFA TMEM11 TMEM14B TMEM19 TMEM237 TMEM248 TMEM42 TMEM50A TMEM50B TMX2 TSNARE1 TSPAN2 TVP23A VAPA YIPF2 ZDHHC15
Entrez ID		2326	23484
HPRD ID		00631	09551
Ensembl ID		ENSG00000010932	ENSG00000104660
Uniprot IDs		A0A024R934 B2RCG5 Q01740	O95214 Q6FHL7
PDB IDs
Enriched GO Terms of Interacting Partners?
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