TBC1D1 and ZFP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TBC1D1	ZFP1
Description		TBC1 domain family member 1	ZFP1 zinc finger protein
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus
	Molecular Function	GTPase Activator Activity Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Intracellular Protein Transport Regulation Of Protein Localization Activation Of GTPase Activity Regulation Of Cilium Assembly	Regulation Of Transcription By RNA Polymerase II
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane	Generic Transcription Pathway
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Amyotrophic lateral sclerosis in C9orf72 mutation negative individuals ( 22959728) Bipolar disorder ( 34099189) Crohn's disease ( 23850713 23266558) Diastolic blood pressure ( 27841878 27618452) Gut microbiota relative abundance (unclassified genus belonging to family Lachnospiraceae) ( 33208821) High-sensitivity cardiac troponin T levels ( 33321125) Lymphocyte counts ( 32888494 27863252) Lymphocyte percentage of white cells ( 32888494 27863252) Monocyte percentage of white cells ( 32888494) Neutrophil percentage of white cells ( 32888494 27863252) Periodontal microbiota ( 22699663) Pulse pressure ( 27841878) Response to antidepressants (symptom remission) ( 29160301) Response to SSRI (symptom remission) ( 29160301) Systolic blood pressure ( 27841878 27618452) Verbal declarative memory ( 25648963) Weight ( 28552196) White blood cell count ( 32888494)	Alcoholic chronic pancreatitis ( 28754779) Eosinophil percentage of white cells ( 32888494) Lymphocyte counts ( 32888494) Pancreatic cancer ( 25086665)
Interacting Genes		31 interacting genes: CALM1 CALM2 CALM3 CCDC185 CWF19L2 EFHC2 FAM161A FAM50B GABARAPL1 GMCL1 HOXC8 HSF2BP HSPB1 KRT75 L3MBTL3 LHX8 LNX1 LZTS1 MAP1LC3A MCRS1 PNKP RIN1 SMAD2 SYTL4 TCEA2 TNNC2 TSGA10IP TXLNA VPS52 YWHAG ZFP1	22 interacting genes: CARD10 CAVIN1 CCDC125 CCDC136 CEP19 CEP70 CIB3 CRLF3 EMD GOLGA6L9 HAP1 HOOK2 KRT40 LDOC1 MAP3K20 MFAP1 MTUS2 POU6F2 TBC1D1 TRIM41 TSPYL2 ZNF250
Entrez ID		23216	162239
HPRD ID		18161	15724
Ensembl ID		ENSG00000065882	ENSG00000184517
Uniprot IDs		B9A6J6 Q6PJJ8 Q86TI0 Q8NC59	H3BV40 J3KNQ1 Q6P2D0
PDB IDs		3QYE
Enriched GO Terms of Interacting Partners?
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